Joris C Verster1, Marlou Mackus2, Aurora Jae van de Loo3, Johan Garssen4, Andrew Scholey5. 1. Utrecht University, Division of Pharmacology, Utrecht, The Netherlands; Utrecht University, Institute for Risk Assessment Sciences, Utrecht, The Netherlands; Swinburne University, Centre for Human Psychopharmacology, Melbourne, Australia. Electronic address: j.c.verster@uu.nl. 2. Utrecht University, Division of Pharmacology, Utrecht, The Netherlands. 3. Utrecht University, Division of Pharmacology, Utrecht, The Netherlands; Utrecht University, Institute for Risk Assessment Sciences, Utrecht, The Netherlands. 4. Utrecht University, Division of Pharmacology, Utrecht, The Netherlands; Nutricia Research, Utrecht, The Netherlands. 5. Utrecht University, Division of Pharmacology, Utrecht, The Netherlands; Swinburne University, Centre for Human Psychopharmacology, Melbourne, Australia.
Abstract
INTRODUCTION: It has been postulated that the hangover state starts when breath alcohol concentration is zero. METHODS: Data from 2 studies that assessed ethanol in breath, blood and urine were compared. RESULTS: The data revealed that ethanol may still be present in the blood and urine during the hangover state, despite breath analyser readings of zero. DISCUSSION: As ethanol is still present in the body despite zero breath alcohol readings, the current consensus to postpone cognitive testing in hangover studies until breath alcohol concentration is zero should be reconsidered.
RCT Entities:
INTRODUCTION: It has been postulated that the hangover state starts when breath alcohol concentration is zero. METHODS: Data from 2 studies that assessed ethanol in breath, blood and urine were compared. RESULTS: The data revealed that ethanol may still be present in the blood and urine during the hangover state, despite breath analyser readings of zero. DISCUSSION: As ethanol is still present in the body despite zero breath alcohol readings, the current consensus to postpone cognitive testing in hangover studies until breath alcohol concentration is zero should be reconsidered.
Authors: Patricia L Darbishire; Patricia S Devine; Alexa J Proctor; Wesley J Horner; Emily M Hoffman; Carol A Ott; David G Fuentes; Jeremy Hughes; Priya B Patel Journal: Am J Pharm Educ Date: 2019-04 Impact factor: 2.047
Authors: Joris C Verster; Aurora J A E van de Loo; Sarah Benson; Andrew Scholey; Ann-Kathrin Stock Journal: J Clin Med Date: 2020-03-13 Impact factor: 4.241