Thanh Cong Bui1, Ly Thi-Hai Tran, Thuy Nhu Thai, Sanjay S Shete, Damon J Vidrine, Erich M Sturgis. 1. From the *Department of Family and Preventative Medicine, The University of Oklahoma Health Sciences Center, Oklahoma City, OK; †Department of Epidemiology, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX; ‡Department of Epidemiology and Biostatistics, College of Public Health, The University of Georgia, Athens, GA; § Division of Quantitative Sciences, Department of Biostatistics, and ¶ Division of Surgery, Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX.
Abstract
BACKGROUND: This study investigated the prevalence of and risk factors for oral human papillomavirus (HPV) infection with multiple genotypes in the United States. METHODS: Data were from the nationally representative 2009-2012 National Health and Nutrition Examination Survey. This analysis comprised 9257 participants for whom data on oral HPV (37 genotypes) and associated risk factors were available. RESULTS: The weighted prevalence of multitype (2-6 types) oral HPV infection was 1.5% (2.5% for men, 0.4% for women) in the whole sample and 19.7% (22.0% for men, 12.1% for women) in those who had any type of oral HPV positivity. Most multitype oral HPV cases (83.8%) harbored one or more oncogenic types. In the adjusted multinominal logistic regression model, being male (relative risk ratio [RRR] = 3.69; 95% confidence interval [CI], 1.57-8.65), being a current cigarette smoker (RRR = 2.57; 95% CI, 1.23-5.36), and having a new sex partner in the past year (RRR = 2.10; 95% CI, 1.03-4.28) were associated with an increased risk of multitype oral HPV infection over single-type HPV infection. CONCLUSIONS: Men, smokers, and those who had new sexual partners were at a significantly higher risk for multitype oral HPV infection.
BACKGROUND: This study investigated the prevalence of and risk factors for oral humanpapillomavirus (HPV) infection with multiple genotypes in the United States. METHODS: Data were from the nationally representative 2009-2012 National Health and Nutrition Examination Survey. This analysis comprised 9257 participants for whom data on oral HPV (37 genotypes) and associated risk factors were available. RESULTS: The weighted prevalence of multitype (2-6 types) oral HPV infection was 1.5% (2.5% for men, 0.4% for women) in the whole sample and 19.7% (22.0% for men, 12.1% for women) in those who had any type of oral HPV positivity. Most multitype oral HPV cases (83.8%) harbored one or more oncogenic types. In the adjusted multinominal logistic regression model, being male (relative risk ratio [RRR] = 3.69; 95% confidence interval [CI], 1.57-8.65), being a current cigarette smoker (RRR = 2.57; 95% CI, 1.23-5.36), and having a new sex partner in the past year (RRR = 2.10; 95% CI, 1.03-4.28) were associated with an increased risk of multitype oral HPV infection over single-type HPV infection. CONCLUSIONS:Men, smokers, and those who had new sexual partners were at a significantly higher risk for multitype oral HPV infection.
Authors: Helen Trottier; Salaheddin Mahmud; Maria Cecilia Costa; João P Sobrinho; Eliane Duarte-Franco; Thomas E Rohan; Alex Ferenczy; Luisa L Villa; Eduardo L Franco Journal: Cancer Epidemiol Biomarkers Prev Date: 2006-07 Impact factor: 4.254
Authors: M L Gillison; W M Koch; R B Capone; M Spafford; W H Westra; L Wu; M L Zahurak; R W Daniel; M Viglione; D E Symer; K V Shah; D Sidransky Journal: J Natl Cancer Inst Date: 2000-05-03 Impact factor: 13.506
Authors: Aimée R Kreimer; Rohini K Bhatia; Andrea L Messeguer; Paula González; Rolando Herrero; Anna R Giuliano Journal: Sex Transm Dis Date: 2010-06 Impact factor: 2.830
Authors: Raphael P Viscidi; Mark Schiffman; Allan Hildesheim; Rolando Herrero; Philip E Castle; Maria C Bratti; Ana Cecilia Rodriguez; Mark E Sherman; Sophia Wang; Barbara Clayman; Robert D Burk Journal: Cancer Epidemiol Biomarkers Prev Date: 2004-02 Impact factor: 4.254
Authors: Salvatore Vaccarella; Silvia Franceschi; Rolando Herrero; Nubia Muñoz; Peter J F Snijders; Gary M Clifford; Jennifer S Smith; Eduardo Lazcano-Ponce; Sukhon Sukvirach; Hai-Rim Shin; Silvia de Sanjosé; Monica Molano; Elena Matos; Catterina Ferreccio; Pham Thi Hoang Anh; Jaiye O Thomas; Chris J L M Meijer Journal: Cancer Epidemiol Biomarkers Prev Date: 2006-02 Impact factor: 4.254