| Literature DB >> 28176160 |
Yi Xu1, Yisuo Sun2, Jinmin Ma2, Shuru Zhou1,3, Wei Fang2, Jiawei Ye1, Limei Tan1, Jingkai Ji2, Dan Luo1, Liqiang Li2, Jiandong Li2, Chunxiao Fang1, Na Pei2, Shuo Shi2, Xin Liu2, Hui Jiang2, Sitang Gong4, Xun Xu5.
Abstract
Enterovirus 96 (EV-96) is a recently described member of the species Enterovirus C and is associated with paralysis and myelitis. In this study, using metagenomic sequencing, we identified a new enterovirus 96 strain (EV-96-SZ/GD/CHN/2014) as the sole pathogen causing hand, foot, and mouth disease (HFMD). A genomic comparison showed that EV-96-SZ/GD/CHN/2014 is most similar to the EV-96-05517 strain (85% identity), which has also been detected in Guangdong Province. This is the first time that metagenomic sequencing has been used to identify an EV-96 strain shown to be associated with HFMD.Entities:
Keywords: Enterovirus 96; Evolution; Genome sequence; HFMD; Metagenomics
Mesh:
Substances:
Year: 2017 PMID: 28176160 DOI: 10.1007/s11262-017-1431-5
Source DB: PubMed Journal: Virus Genes ISSN: 0920-8569 Impact factor: 2.332