| Literature DB >> 28174765 |
Rupesh E Patre1, Sanjib Mal1, Pankaj R Nilkanth1, Sujit K Ghorai1, Sudhindra H Deshpande1, Myriem El Qacemi2, Tomas Smejkal2, Sitaram Pal1, Bhanu N Manjunath1.
Abstract
A bio-catalyzed N-formylation reaction of different amines has been developed using ethyl formate as a formylating agent. This protocol provides a facile and convenient strategy featuring mild reaction conditions, high efficacy, a broad substrate scope and recyclability of lipase. This method also works on a large scale in high yield.Entities:
Year: 2017 PMID： 28174765 DOI： 10.1039/c6cc07679c
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222