Literature DB >> 28171745

Breaking Down Neighbors to Fuel Tumorigenesis.

John Vaughen1, Tatsushi Igaki2.   

Abstract

Autophagy supports cell growth and survival autonomously by recycling intracellular proteins and/or organelles. Reporting in Nature, Katheder and colleagues (2017) find that tumors trigger non-autonomous autophagy in neighboring cells and distant organs, thus fueling tumor growth and metastasis. This opens new avenues for understanding and manipulating cancers through cell-cell communication.
Copyright © 2017 Elsevier Inc. All rights reserved.

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Mesh：

Year:  2017        PMID： 28171745      PMCID： PMC6207202          DOI： 10.1016/j.devcel.2017.01.011

Source DB:  PubMed          Journal:  Dev Cell        ISSN： 1534-5807            Impact factor:   12.270


  10 in total

1.  A genetic screen in Drosophila for metastatic behavior.

Authors:  Raymond A Pagliarini; Tian Xu
Journal:  Science       Date:  2003-10-09       Impact factor: 47.728

2.  Supercompetitor status of Drosophila Myc cells requires p53 as a fitness sensor to reprogram metabolism and promote viability.

Authors:  Claire de la Cova; Nanami Senoo-Matsuda; Marcello Ziosi; D Christine Wu; Paola Bellosta; Catarina M Quinzii; Laura A Johnston
Journal:  Cell Metab       Date:  2014-02-20       Impact factor: 27.287

3.  Microenvironmental autophagy promotes tumour growth.

Authors:  Nadja S Katheder; Rojyar Khezri; Fergal O'Farrell; Sebastian W Schultz; Ashish Jain; Mohammed M Rahman; Kay O Schink; Theodossis A Theodossiou; Terje Johansen; Gábor Juhász; David Bilder; Andreas Brech; Harald Stenmark; Tor Erik Rusten
Journal:  Nature       Date:  2017-01-11       Impact factor: 49.962

4.  An Ectopic Network of Transcription Factors Regulated by Hippo Signaling Drives Growth and Invasion of a Malignant Tumor Model.

Authors:  Mardelle Atkins; Delphine Potier; Lucia Romanelli; Jelle Jacobs; Jana Mach; Fisun Hamaratoglu; Stein Aerts; Georg Halder
Journal:  Curr Biol       Date:  2016-07-28       Impact factor: 10.834

5.  Malignant Drosophila tumors interrupt insulin signaling to induce cachexia-like wasting.

Authors:  Alejandra Figueroa-Clarevega; David Bilder
Journal:  Dev Cell       Date:  2015-04-06       Impact factor: 12.270

Review 6.  Cancer metabolism: a therapeutic perspective.

Authors:  Ubaldo E Martinez-Outschoorn; Maria Peiris-Pagés; Richard G Pestell; Federica Sotgia; Michael P Lisanti
Journal:  Nat Rev Clin Oncol       Date:  2016-05-04       Impact factor: 66.675

7.  Autophagy regulates tissue overgrowth in a context-dependent manner.

Authors:  E Pérez; G Das; A Bergmann; E H Baehrecke
Journal:  Oncogene       Date:  2014-09-01       Impact factor: 9.867

Review 8.  Non-autonomous overgrowth by oncogenic niche cells: Cellular cooperation and competition in tumorigenesis.

Authors:  Masato Enomoto; John Vaughen; Tatsushi Igaki
Journal:  Cancer Sci       Date:  2015-10-16       Impact factor: 6.716

Review 9.  Recent insights into the function of autophagy in cancer.

Authors:  Ravi Amaravadi; Alec C Kimmelman; Eileen White
Journal:  Genes Dev       Date:  2016-09-01       Impact factor: 11.361

10.  Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion.

Authors:  Cristovão M Sousa; Douglas E Biancur; Xiaoxu Wang; Christopher J Halbrook; Mara H Sherman; Li Zhang; Daniel Kremer; Rosa F Hwang; Agnes K Witkiewicz; Haoqiang Ying; John M Asara; Ronald M Evans; Lewis C Cantley; Costas A Lyssiotis; Alec C Kimmelman
Journal:  Nature       Date:  2016-08-10       Impact factor: 49.962
  10 in total

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