Literature DB >> 28168816

Lactate levels and pneumonia severity index are good predictors of in-hospital mortality in pneumonia.

Bulut Demirel1.   

Abstract

INTRODUCTION: Pneumonia is an inflammatory disease caused by micro-organisms. The pneumonia severity index (PSI) and CURB_65 scores are widely used to predict the mortality risk. We wanted to calculate the value of lactic acid level in predicting the mortality risk.
MATERIALS AND METHODS: This prospective cross-sectional study performed in a third level education and research hospital. The pneumonia diagnosis was determined by symptoms, physical examination findings, and radiological findings.
RESULTS: The mean age of the patients was 71.0 ± 16.5. The overall mortality rate was 21.8%. The mean lactate level was 3.53 ± 3.59. Lactate is significantly higher in patients who were died. The PSI and CURB_65 scores were higher in patients who died. The cutoff value of lactate level for mortality is 3.35 mmol/mm3. The cutoff point of PSI for mortality was 148.5 points; equal or over this point the mortality rate is 90.9%. DISCUSSION: The early prediction of the mortality risk is important to determine the high risk patients to hospitalize in intensive care unit and close follow up. The lactate level, PSI score and CURB_65 scores are good predictors for mortality. We can use them in emergency departments for risk stratification.
© 2017 John Wiley & Sons Ltd.

Entities:  

Keywords:  CURB_65; lactate; mortality; pneumonia; pneumonia severity index

Mesh:

Substances:

Year:  2017        PMID: 28168816     DOI: 10.1111/crj.12616

Source DB:  PubMed          Journal:  Clin Respir J        ISSN: 1752-6981            Impact factor:   2.570


  4 in total

1.  Handheld Point-of-Care Lactate Measurement at Admission Predicts Mortality in Ugandan Children Hospitalized with Pneumonia: A Prospective Cohort Study.

Authors:  Cary Ma; Lourdes Cynthia Gunaratnam; Austin Ericson; Andrea L Conroy; Sophie Namasopo; Robert O Opoka; Michael T Hawkes
Journal:  Am J Trop Med Hyg       Date:  2019-01       Impact factor: 2.345

2.  Association of Different Lactate Indices with 30-Day and 180-Day Mortality in Patients with ST-Segment Elevation Myocardial Infarction Treated with Primary Percutaneous Coronary Intervention: A Retrospective Cohort Study.

Authors:  Long Hu; Wei Lin; Tiancheng Xu; Dongjie Liang; Guangze Xiang; Rujie Zheng; Changzuan Zhou; Qinxue Dai; Danyun Jia
Journal:  Ther Clin Risk Manag       Date:  2020-09-02       Impact factor: 2.423

3.  Stratified and prognostic value of admission lactate and severity scores in patients with community-acquired pneumonia in emergency department: A single-center retrospective cohort study.

Authors:  Haijiang Zhou; Tianfei Lan; Shubin Guo
Journal:  Medicine (Baltimore)       Date:  2019-10       Impact factor: 1.817

4.  Comparison of clinical features and prognosis in patients with cryptogenic and secondary organizing pneumonia.

Authors:  Keum-Ju Choi; Eun-Hyung Yoo; Kyung Chan Kim; Eun Jin Kim
Journal:  BMC Pulm Med       Date:  2021-10-29       Impact factor: 3.317

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.