Nada Sulaiman1, Jeanette Soon2, Jong Kwan Park3, Christopher Naoum4, Shaw-Hua Kueh5, Philipp Blanke6, Darra Murphy7, Jennifer Ellis8, Cameron J Hague9, Jonathon Leipsic10. 1. St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: sulaimannada@gmail.com. 2. St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: jeanette.soon@gmail.com. 3. St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: jongknpark@gmail.com. 4. St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: chris.naoum@gmail.com. 5. St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: sh_kueh@hotmail.com. 6. St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: phil.blanke@gmail.com. 7. St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: darramurphy@me.com. 8. St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: ellisjen19@gmail.com. 9. St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: cjhague75@gmail.com. 10. St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: jleipsic@providencehealth.bc.ca.
Abstract
INTRODUCTION: We sought to validate whether low dose CACS CT with hybrid IR (HIR) could replace standard dose filtered back projection (FBP). METHOD: We enrolled 100 patients to undergo low dose CACS CT with HIR, in addition to routine full dose FBP. RESULTS: No significant difference between full and low dose CT in Agatston score 138.2±360.6 vs. 137.3±356.4 (p=0.272) or calcium mass score 19±48.3 vs. 18.7±49 (p=0.8), respectively. Bland-Altman analysis showed no systematic bias. Calcium volume difference was statistically significant 57.2±134 vs. 55.1±130.2 (p=0.001). CONCLUSION: Low dose CT for calcium scoring with HIR enables stable CACS Agatston score and calcium mass quantification as compared to full dose FBP.
INTRODUCTION: We sought to validate whether low dose CACS CT with hybrid IR (HIR) could replace standard dose filtered back projection (FBP). METHOD: We enrolled 100 patients to undergo low dose CACS CT with HIR, in addition to routine full dose FBP. RESULTS: No significant difference between full and low dose CT in Agatston score 138.2±360.6 vs. 137.3±356.4 (p=0.272) or calcium mass score 19±48.3 vs. 18.7±49 (p=0.8), respectively. Bland-Altman analysis showed no systematic bias. Calcium volume difference was statistically significant 57.2±134 vs. 55.1±130.2 (p=0.001). CONCLUSION: Low dose CT for calcium scoring with HIR enables stable CACS Agatston score and calcium mass quantification as compared to full dose FBP.
Authors: N R van der Werf; P A Rodesch; S Si-Mohamed; R W van Hamersvelt; M J W Greuter; T Leiner; L Boussel; M J Willemink; P Douek Journal: Eur Radiol Date: 2022-01-08 Impact factor: 5.315