Literature DB >> 28165174

Virus-Mimetic Fusogenic Exosomes for Direct Delivery of Integral Membrane Proteins to Target Cell Membranes.

Yoosoo Yang1, Yeonsun Hong1,2, Gi-Hoon Nam1,2, Jin Hwa Chung3, Eunee Koh1,2, In-San Kim1,2.   

Abstract

An efficient system for direct delivery of integral membrane proteins is successfully developed using a new biocompatible exosome-based platform. Fusogenic exosomes harboring viral fusogen, vascular stomatitis virus (VSV)-G protein, can fuse with and modify plasma membranes in a process called "membrane editing." This can facilitate the transfer of biologically active membrane proteins into the target cell membranes both in vitro and in vivo.
© 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  exosomes; membrane protein; nanoplatform; viral fusogen

Mesh：

Substances：

Year:  2017        PMID： 28165174     DOI： 10.1002/adma.201605604

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  27 in total

Review 1.  Human Pluripotent Stem Cell-Derived Extracellular Vesicles: Characteristics and Applications.

Authors:  Richard Jeske; Julie Bejoy; Mark Marzano; Yan Li
Journal:  Tissue Eng Part B Rev       Date:  2020-01-16       Impact factor: 6.389

2.  Expanding the toolbox of exosome-based modulators of cell functions.

Authors:  Qinqin Cheng; Zhefu Dai; Xiaojing Shi; Xinping Duan; Yiling Wang; Tianling Hou; Yong Zhang
Journal:  Biomaterials       Date:  2021-09-12       Impact factor: 15.304

Review 3.  Extracellular vesicles as bioactive nanotherapeutics: An emerging paradigm for regenerative medicine.

Authors:  Min Li; Fang Fang; Meng Sun; Yinfeng Zhang; Min Hu; Jinfeng Zhang
Journal:  Theranostics       Date:  2022-06-21       Impact factor: 11.600

4.  Preparation of cationic proteoliposomes using cell-free membrane protein synthesis: the chaperoning effect of cationic liposomes.

Authors:  Mitsuru Ando; Yoshihiro Sasaki; Kazunari Akiyoshi
Journal:  RSC Adv       Date:  2020-08-04       Impact factor: 4.036

Review 5.  Exosome Theranostics: Biology and Translational Medicine.

Authors:  Chuanjiang He; Shu Zheng; Yan Luo; Ben Wang
Journal:  Theranostics       Date:  2018-01-01       Impact factor: 11.556

Review 6.  Extracellular vesicles as a platform for membrane-associated therapeutic protein delivery.

Authors:  Yoosoo Yang; Yeonsun Hong; Eunji Cho; Gi Beom Kim; In-San Kim
Journal:  J Extracell Vesicles       Date:  2018-03-01

7.  Extracellular vesicles expressing a single-chain variable fragment of an HIV-1 specific antibody selectively target Env+ tissues.

Authors:  Xue Zou; Meng Yuan; Tongyu Zhang; Hongxia Wei; Shijie Xu; Na Jiang; Nan Zheng; Zhiwei Wu
Journal:  Theranostics       Date:  2019-07-29       Impact factor: 11.556

8.  CD103-positive CSC exosome promotes EMT of clear cell renal cell carcinoma: role of remote MiR-19b-3p.

Authors:  Lu Wang; Guang Yang; Danfeng Zhao; Jiaqi Wang; Yang Bai; Qiang Peng; Hongzhi Wang; Ruizhe Fang; Guang Chen; Zhichao Wang; Keliang Wang; Guangbin Li; Yinhui Yang; Ziqi Wang; Pengyu Guo; Li Peng; Dayong Hou; Wanhai Xu
Journal:  Mol Cancer       Date:  2019-04-11       Impact factor: 27.401

Review 9.  Engineering Cell Membrane-Based Nanotherapeutics to Target Inflammation.

Authors:  Huize Yan; Dan Shao; Yeh-Hsing Lao; Mingqiang Li; Hanze Hu; Kam W Leong
Journal:  Adv Sci (Weinh)       Date:  2019-05-22       Impact factor: 16.806

Review 10.  Regulatory Role of Immune Cell-Derived Extracellular Vesicles in Cancer: The Message Is in the Envelope.

Authors:  Chi Li; Howard Donninger; John Eaton; Kavitha Yaddanapudi
Journal:  Front Immunol       Date:  2020-07-16       Impact factor: 7.561
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