Literature DB >> 28165145

Left ventricular diastolic dysfunction in patients with chronic obstructive pulmonary disease: Impact of methods of assessment.

Heba Farouk1, Maged Albasmi1, Karim El Chilali2, Kareem Mahmoud1, Abdo Nasr1, Hussein Heshmat1, Samah Abdel-Moneim3, Essam Baligh1.   

Abstract

BACKGROUND: The prevalence of left ventricular (LV) diastolic dysfunction in patients with chronic obstructive pulmonary disease (COPD), using different echocardiographic parameters, varies widely in the literature. The highest prevalence of LV diastolic dysfunction was detected using the mitral inflow indexes that are commonly altered in these patients due to the associated tachycardia, reduced preload, and ventricular septal shift. In this study, we aimed at evaluating the impact of the used echocardiographic method of assessment on the prevalence of LV diastolic dysfunction in patients with COPD and normal LV systolic function.
METHODS: We studied 35 patients with COPD and 18 age-matched controls. A comprehensive approach to diagnose and grade the LV diastolic dysfunction was performed in accordance with the recommendations of the American Society of Echocardiography published in 2009. The results were compared with those of mitral inflow indexes.
RESULTS: LV diastolic dysfunction was reported in 20 patients using the mitral inflow indexes while in only 12 patients using the comprehensive approach (P=.021). Compared to the controls, LV diastolic dysfunction was significantly more common in patients using the mitral inflow indexes (P=.001), while no statistically significant difference was detected between both groups using the comprehensive approach (P=.1).
CONCLUSION: The prevalence of LV diastolic dysfunction in patients with COPD varies according to the used echocardiographic approach. Further studies are recommended to determine which approach is the most accurate in estimating the true prevalence of LV diastolic dysfunction among this group of patients.
© 2017, Wiley Periodicals, Inc.

Entities:  

Keywords:  chronic obstructive pulmonary disease; left ventricular diastolic function; mitral inflow indexes; tissue Doppler imaging

Mesh:

Year:  2017        PMID: 28165145     DOI: 10.1111/echo.13469

Source DB:  PubMed          Journal:  Echocardiography        ISSN: 0742-2822            Impact factor:   1.724


  3 in total

1.  Rethinking Chronic Obstructive Pulmonary Disease. Chronic Pulmonary Insufficiency and Combined Cardiopulmonary Insufficiency.

Authors:  R Graham Barr
Journal:  Ann Am Thorac Soc       Date:  2018-02

2.  Diastolic Dysfunction in Patients with Chronic Obstructive Pulmonary Disease: A Meta-Analysis of Case Controlled Studies.

Authors:  Angelina Zhyvotovska; Denis Yusupov; Haroon Kamran; Tarik Al-Bermani; Rishard Abdul; Samir Kumar; Nikita Mogar; Angeleque Hartt; Louis Salciccioli; Samy I McFarlane
Journal:  Int J Clin Res Trials       Date:  2019-09-19

3.  Increased MMP8 Levels in Atopic Chronic Obstructive Pulmonary Disease: A Study Testing Multiple Immune Factors in Atopic and Non-Atopic Patients.

Authors:  Haisheng Hu; Chuanxu Cai; Huimin Huang; Mingshan Xue; Jiaying Luo; Chenxi Liao; Baoqing Sun
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2020-07-30
  3 in total

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