| Literature DB >> 28164853 |
Michael A Silverman1, Liza Konnikova2, Jeffrey S Gerber3.
Abstract
Antibiotic treatment alters the composition and metabolic function of the intestinal microbiota. These alterations may contribute to the pathogenesis of necrotizing enterocolitis (NEC) and antibiotic-associated diarrhea (AAD). Recent studies are beginning to unravel the contribution of specific groups of microbes and their metabolic pathways to these diseases. Probiotics or other microbiota-targeted therapies may provide effect strategies to prevent and treat NEC and AAD.Entities:
Keywords: Antibiotic-associated diarrhea; Antibiotics; Clostridium difficile; Microbiome; Necrotizing enterocolitis; Probiotics
Mesh:
Substances:
Year: 2017 PMID: 28164853 PMCID: PMC5314436 DOI: 10.1016/j.gtc.2016.09.010
Source DB: PubMed Journal: Gastroenterol Clin North Am ISSN: 0889-8553 Impact factor: 3.806