Literature DB >> 28163912

The benefits of youth are lost on the young cardiac arrest patient.

Brian Griffith1, Patrick Kochanek2, Cameron Dezfulian3.   

Abstract

Children and young adults tend to have reduced mortality and disability after acquired brain injuries such as trauma or stroke and across other disease processes seen in critical care medicine. However, after out-of-hospital cardiac arrest (OHCA), outcomes are remarkably similar across age groups. The consistent lack of witnessed arrests and a high incidence of asphyxial or respiratory etiology arrests among pediatric and young adult patients with OHCA account for a substantial portion of the difference in outcomes. Additionally, in younger children, differences in pre-hospital response and the activation of developmental apoptosis may explain more severe outcomes after OHCA. These require us to consider whether present practices are in line with the science. The present recommendations for compression-only cardiopulmonary resuscitation in young adults, normothermia as opposed to hypothermia (33°C) after asphyxial arrests, and paramedic training are considered within this review in light of existing evidence. Modifications in present standards of care may help restore the benefits of youth after brain injury to the young survivor of OHCA.

Entities:  

Keywords:  Cardiac arrest; Paediatric; Resuscitation

Year:  2017        PMID: 28163912      PMCID: PMC5270587          DOI: 10.12688/f1000research.9316.1

Source DB:  PubMed          Journal:  F1000Res        ISSN: 2046-1402


  78 in total

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Authors:  Michael Hüpfl; Harald F Selig; Peter Nagele
Journal:  Lancet       Date:  2010-10-14       Impact factor: 79.321

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Journal:  Circulation       Date:  2015-11-03       Impact factor: 29.690

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Authors:  Kaustubha D Patil; Henry R Halperin; Lance B Becker
Journal:  Circ Res       Date:  2015-06-05       Impact factor: 17.367

4.  Socioeconomic factors associated with outcome after cardiac arrest in patients under the age of 65.

Authors:  Thomas Uray; Florian B Mayr; James Fitzgibbon; Jon C Rittenberger; Clifton W Callaway; Tomas Drabek; Anthony Fabio; Derek C Angus; Patrick M Kochanek; Cameron Dezfulian
Journal:  Resuscitation       Date:  2015-05-21       Impact factor: 5.262

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Journal:  Circulation       Date:  2015-11-03       Impact factor: 29.690

6.  Long term survival after primary intracerebral haemorrhage: a retrospective population based study.

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7.  Continuous improvements in "chain of survival" increased survival after out-of-hospital cardiac arrests: a large-scale population-based study.

Authors:  Taku Iwami; Graham Nichol; Atsushi Hiraide; Yasuyuki Hayashi; Tatsuya Nishiuchi; Kentaro Kajino; Hiroshi Morita; Hidekazu Yukioka; Hisashi Ikeuchi; Hisashi Sugimoto; Hiroshi Nonogi; Takashi Kawamura
Journal:  Circulation       Date:  2009-01-26       Impact factor: 29.690

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Authors:  Catherine E Creeley; John W Olney
Journal:  Anesth Analg       Date:  2009-12-02       Impact factor: 5.108

9.  Increasing cumulative exposure to volatile anesthetic agents is associated with poorer neurodevelopmental outcomes in children with hypoplastic left heart syndrome.

Authors:  Laura K Diaz; J William Gaynor; Shannon J Koh; Richard F Ittenbach; Marsha Gerdes; Judy C Bernbaum; Elaine H Zackai; Robert R Clancy; Mohamed A Rehman; Jeffrey W Pennington; Nancy Burnham; Thomas L Spray; Susan C Nicolson
Journal:  J Thorac Cardiovasc Surg       Date:  2016-04-18       Impact factor: 5.209

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Authors:  Johan Engdahl; Asa Axelsson; Angela Bång; Björn W Karlson; Johan Herlitz
Journal:  Resuscitation       Date:  2003-08       Impact factor: 5.262

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