Literature DB >> 28162881

Midterm results of osteochondral allograft transplantation to the humeral head.

Andrew J Riff1, Adam B Yanke2, Jason J Shin3, Anthony A Romeo2, Brian J Cole2.   

Abstract

BACKGROUND: This study evaluated clinical outcomes of osteochondral allograft (OCA) transplantation for humeral head osteochondral defects. We hypothesized that patients with isolated humeral head disease would achieve favorable results and that patients with bipolar disease would experience inferior outcomes.
METHODS: We identified patients who underwent humeral head OCA transplantation. Subjective questionnaire data were obtained preoperatively and at a minimum of 2 years postoperatively. Radiographs were evaluated for graft incorporation. Failure was defined by conversion to shoulder arthroplasty, American Shoulder and Elbow Surgeons score <50, or dissatisfaction with the surgical result.
RESULTS: Twenty patients (65% male) met inclusion criteria. Patients were an average age of 24.8 ± 8.1 years. Eleven patients underwent concomitant glenoid surgery (microfracture or meniscal allograft resurfacing). Follow-up was available for 18 patients (90%) at mean of 67 months. All grafts incorporated except 2. Four patients underwent shoulder arthroplasty at mean of 25 months postoperatively (all after pain pump chondrolysis). Eleven of the 20 patients were satisfied (all dissatisfied patients underwent glenoid surgery). Significant improvements (P < .001) were seen for the visual analog scale (from 6.1 to 1.5), Simple Shoulder Test (from 32 to 73), American Shoulder and Elbow Surgeons score (from 39 to 76), and the physical component of the 12-Item Short Form Survey (from 38 to 48). Pain pump patients who did not progress to arthroplasty experienced inferior satisfaction (40% vs. 87.5%, P = .04) and a trend toward inferior outcomes compared with the rest of the cohort.
CONCLUSION: OCA transplantation is a viable option for young patients with isolated humeral chondral injury. Patients with bipolar disease or a history of intra-articular pain pump have increased failure and decreased subjective outcomes.
Copyright © 2016 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  cartilage restoration; chondrolysis; humeral head; osteochondral allograft; osteochondral defect; shoulder

Mesh:

Year:  2017        PMID: 28162881     DOI: 10.1016/j.jse.2016.11.053

Source DB:  PubMed          Journal:  J Shoulder Elbow Surg        ISSN: 1058-2746            Impact factor:   3.019


  12 in total

1.  Biologic Characteristics of Shoulder Articular Cartilage in Comparison to Knee and Ankle Articular Cartilage From Individual Donors.

Authors:  Susanna Chubinskaya; Eric J Cotter; Rachel M Frank; Arnavaz A Hakimiyan; Adam B Yanke; Brian J Cole
Journal:  Cartilage       Date:  2019-05-14       Impact factor: 4.634

2.  Fresh Osteochondral Allograft Transplantation for Focal Chondral Defect of the Humerus Associated With Anchor Arthropathy and Failed SLAP Repair.

Authors:  Kevin C Wang; Brian R Waterman; Eric J Cotter; Rachel M Frank; Brian J Cole
Journal:  Arthrosc Tech       Date:  2017-08-28

3.  The GLAD Lesion: are the definition, diagnosis and treatment up to date? A Systematic Review.

Authors:  Giuseppe Porcellini; Antonio Benedetto Cecere; Andrea Giorgini; Gian Mario Micheloni; Luigi Tarallo
Journal:  Acta Biomed       Date:  2020-12-30

4.  The "BioHumi" Humeral Head Elliptical Osteochondral Allograft Transplantation.

Authors:  Eric E Peterson; Paul E Caldwell; Sara E Pearson
Journal:  Arthrosc Tech       Date:  2021-09-21

5.  Combined Double-Pulley Remplissage and Bankart Repair.

Authors:  Dong Hyeon Kim; Joo Yeon Kim; Juho Park; Mika Talwar; Sarah Jenkins; Brandon Gardner; Patrick McGahan; James L Chen
Journal:  Arthrosc Tech       Date:  2022-02-18

6.  Fresh Osteochondral Allograft Transplantation in the Knee: A Viability and Histologic Analysis for Optimizing Graft Viability and Expanding Existing Standard Processed Graft Resources Using a Living Donor Cartilage Program.

Authors:  Mario Hevesi; Janet M Denbeigh; Carlo A Paggi; Catalina Galeano-Garces; Leila Bagheri; A Noelle Larson; Michael J Stuart; Daniel B F Saris; Andre J van Wijnen; Aaron J Krych
Journal:  Cartilage       Date:  2019-10-16       Impact factor: 3.117

7.  Articular Cartilage Defects of the Glenohumeral Joint: A Systematic Review of Treatment Options and Outcomes.

Authors:  Anthony Fiegen; Devin P Leland; Christopher D Bernard; Aaron J Krych; Jonathan D Barlow; Diane L Dahm; Christopher L Camp
Journal:  Cartilage       Date:  2019-08-23       Impact factor: 3.117

Review 8.  Use of Allografts in Orthopaedic Surgery: Safety, Procurement, Storage, and Outcomes.

Authors:  Adam J Beer; Tracy M Tauro; Michael L Redondo; David R Christian; Brian J Cole; Rachel M Frank
Journal:  Orthop J Sports Med       Date:  2019-12-30

9.  Assessment of Safe Cartilage Harvesting Quantity in the Shoulder: A Cadaveric Study.

Authors:  Michael C O'Brien; Wojciech K Dzieza; Michelle L Bruner; Kevin W Farmer
Journal:  Arthrosc Sports Med Rehabil       Date:  2020-12-26

10.  Harvest, Transport, and Storage of Fresh Humeral Head Osteochondral Allograft: Step-by-Step Protocol.

Authors:  Rodrigo Souto Borges Petros; Rafael Augusto Dantas Prinz; Rodrigo Ribeiro Pinho Rodarte; Diego Pinheiro Aguiar; Eduardo Branco de Sousa
Journal:  Arthrosc Tech       Date:  2021-06-20
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