Literature DB >> 2816136

[The question of medullomyoblastoma].

S Patt1, F Oppel, J Cervós-Navarro.   

Abstract

We report a 7 year old female presenting with a primary sarcoma of the frontal cortex, spinal cord metastases, and a cerebellar tumor. The latter was comprised of undifferentiated small cells and a component resembling rhabdomyosarcoma. On formal grounds it could be diagnosed either as medullomyoblastoma or rhabdomyosarcoma. At the ultrastructural level the tumor appeared more typical for a medullomyoblastoma but it seem highly improbable that both (rare) tumors appeared simultaneously by coincidence. Rather, we assume that we are dealing with a metastasis of the sarcoma with differentiation towards rhabdomyosarcoma. The apparent ability of a sarcoma to imitate morphological features of medullomyoblastoma in the cerebellum is further proof of the fact that nosological differentiation of both tumors remains a problem. Our findings did not corroborate the concept of medullomyoblastoma as a separate nosological entity.

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Mesh:

Year:  1989        PMID: 2816136

Source DB:  PubMed          Journal:  Zentralbl Allg Pathol        ISSN: 0044-4030


  3 in total

1.  Cerebellar medullomyoblastoma with advanced neuronal differentiation and hamartomatous component.

Authors:  T Höll; P Kleihues; M G Yasargil; O D Wiestler
Journal:  Acta Neuropathol       Date:  1991       Impact factor: 17.088

2.  Age-related immunoreactivity pattern in medulloblastoma.

Authors:  S Patt; C Zimmer
Journal:  Childs Nerv Syst       Date:  1992-09       Impact factor: 1.475

3.  Medullomyoblastoma: report of two cases.

Authors:  D Schiffer; M T Giordana; S Pezzotta; T Pezzulo; M C Vigliani
Journal:  Childs Nerv Syst       Date:  1992-08       Impact factor: 1.475

  3 in total

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