Literature DB >> 28160337

Relay Drug Delivery for Amplifying Targeting Signal and Enhancing Anticancer Efficacy.

Quanyin Hu1,2, Wujin Sun1,2, Chenggen Qian1,2,3, Hunter N Bomba1,2, Hongliang Xin1,2, Zhen Gu1,2,4.   

Abstract

A "relay drug delivery" system based on two distinct modules, which is composed of a signal transmission nanocarrier A (NCA ) that can specifically induce tumor blood vessel inflammation generation and an execution biomimetic nanocarrier B (NCB ) that can accumulate at the tumor site by receiving the broadcasting signals generated by NCA , is developed for amplifying active tumor targeting signal and enhancing antitumor therapy.
© 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  active targeting; amplification; biomimetic; drug delivery; inflammation

Mesh：

Substances：

Year:  2017        PMID： 28160337     DOI： 10.1002/adma.201605803

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  14 in total

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