Hung-Che Lin1, Yu-Ching Chou2, Chih-Hung Wang1, Li-Wen Hung1, Cheng-Ping Shih1, Bor-Hwang Kang3, Wen-Ying Yeh1, Hsin-Chien Chen4. 1. Department of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan. 2. School of Public Health, National Defense Medical Center, Taipei, Taiwan. 3. Department of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan; Department of Otolaryngology-Head and Neck Surgery, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan. 4. Department of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan. Electronic address: acolufreia@yahoo.com.tw.
Abstract
OBJECTIVE: To investigate the latency and amplitude of auditory brainstem response (ABR) and hearing prognosis in patients with idiopathic sudden sensorineural hearing loss (ISSNHL). METHODS: Patients with ISSNHL were classified into four different recovery groups. All patients' clinical and demographic features were analyzed. Two-channel ABRs were collected in response to click stimuli at 90dB nHL. ABR amplitudes for wave I and ABR latency for waves I, III, and V were analyzed. RESULTS: One hundred and two patients (54 men and 48 women) were included in the study. Hearing recovery was observed in 72 cases (70.6%). Waves I, III, and V latencies were significantly prolonged in the affected ears compared with the unaffected ears. A smaller wave I amplitude was found in the affected ear compared with the unaffected ear in the three recovery groups. There was a significant association between wave I latency and hearing outcome (p=0.009) with a prolonged trend from complete to slight hearing recovery group. CONCLUSIONS: There was a significant correlation between wave I latency and hearing outcome in patients with ISSNHL. The finding may provide diagnostic information and serve as a potential prognostic indicator in patients with ISSNHL.
OBJECTIVE: To investigate the latency and amplitude of auditory brainstem response (ABR) and hearing prognosis in patients with idiopathic sudden sensorineural hearing loss (ISSNHL). METHODS:Patients with ISSNHL were classified into four different recovery groups. All patients' clinical and demographic features were analyzed. Two-channel ABRs were collected in response to click stimuli at 90dB nHL. ABR amplitudes for wave I and ABR latency for waves I, III, and V were analyzed. RESULTS: One hundred and two patients (54 men and 48 women) were included in the study. Hearing recovery was observed in 72 cases (70.6%). Waves I, III, and V latencies were significantly prolonged in the affected ears compared with the unaffected ears. A smaller wave I amplitude was found in the affected ear compared with the unaffected ear in the three recovery groups. There was a significant association between wave I latency and hearing outcome (p=0.009) with a prolonged trend from complete to slight hearing recovery group. CONCLUSIONS: There was a significant correlation between wave I latency and hearing outcome in patients with ISSNHL. The finding may provide diagnostic information and serve as a potential prognostic indicator in patients with ISSNHL.
Authors: Laura Jacxsens; Joke De Pauw; Emilie Cardon; Annemarie van der Wal; Laure Jacquemin; Annick Gilles; Sarah Michiels; Vincent Van Rompaey; Marc J W Lammers; Willem De Hertogh Journal: Front Neurol Date: 2022-08-22 Impact factor: 4.086
Authors: Rahul Mittal; Nicole Bencie; James M Parrish; George Liu; Jeenu Mittal; Denise Yan; Xue Zhong Liu Journal: Front Genet Date: 2018-02-08 Impact factor: 4.599