| Literature DB >> 28157500 |
Elena Torlai Triglia1, Tiago Rito1, Ana Pombo2.
Abstract
Polycomb proteins are well-known epigenetic repressors with unexplained roles in chromatin folding. In this issue of Molecular Cell, Kundu et al. (2017) investigate the structures of PRC1-mediated domains in stem cells and probe their changes upon differentiation and in PRC knockouts.Entities:
Keywords: 5C; PRC1-mediated domains; Phc1; Polycomb bodies; Polycomb repressive complex; STORM; chromatin folding; embryonic stem cells; genome architecture; neural progenitors
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Year: 2017 PMID： 28157500 DOI： 10.1016/j.molcel.2017.01.028
Source DB: PubMed Journal: Mol Cell ISSN： 1097-2765 Impact factor: 17.970