Wei Yu1, Xiaodong Guo2. 1. Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430022, China. 2. Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430022, China. xiaodongguo@hust.edu.cn.
Abstract
PURPOSE: Management of fracture nonunion is challenging as another surgical intervention for the patient is often a necessity, which has a huge impact on both quality of life and economic burden of the patient. Thus, a less aggressive and better accepted treatment for nonunion is required. METHODS: We gave teriparatide to a 45-year-old man with femoral fracture nonunion 1 year after he underwent surgery with autogenous bone grafting that failed to heal his initial nonunion. Successful union was obtained after once-daily administration of teriparatide for 9 months. RESULTS: Our case showed teriparatide could successfully treat a femoral fracture nonunion that autogenous bone grafting failed to heal. CONCLUSIONS: Teriparatide may provide an alternative treatment for fracture nonunion.
PURPOSE: Management of fracture nonunion is challenging as another surgical intervention for the patient is often a necessity, which has a huge impact on both quality of life and economic burden of the patient. Thus, a less aggressive and better accepted treatment for nonunion is required. METHODS: We gave teriparatide to a 45-year-old man with femoral fracture nonunion 1 year after he underwent surgery with autogenous bone grafting that failed to heal his initial nonunion. Successful union was obtained after once-daily administration of teriparatide for 9 months. RESULTS: Our case showed teriparatide could successfully treat a femoral fracture nonunion that autogenous bone grafting failed to heal. CONCLUSIONS:Teriparatide may provide an alternative treatment for fracture nonunion.