Literature DB >> 28155097

Gene Editing, Enhancing and Women's Role.

Frida Simonstein1.   

Abstract

A recent article on the front page of The Independent (September 18, 2015) reported that the genetic 'manipulation' of IVF embryos is to start in Britain, using a new revolutionary gene-editing technique, called Crispr/Cas9. About three weeks later (Saturday 10, October 2015), on the front page of the same newspaper, it was reported that the National Health Service (NHS) faces a one billion pound deficit only 3 months into the new year. The hidden connection between these reports is that gene editing could be used to solve issues related to health care allocation. Improving the health of future generations might coincide with public health goals; it might improve the health of individuals and communities, and, if successful, might be seen as a public good. However, enhancing future generations will require In Vitro Fertilisation and Pre-implantation Genetic Diagnosis. Remarkably, the necessary involvement of women in an enhancing scenario has not been discussed by its proponents. The present discourse on moral obligations of future generations, although not referring to women, seems to imply that women might be required, morally, if not legally, to reproduce with IVF. Enhancing future generations will be gendered, unless the artificial womb is developed. These are challenging issues that require a wider perspective, of both women and men. Despite the lack of a unified feminist conclusion in the discussions about the merits and risks of human genome modification, there is an urgent need to clarify the role of women in this scenario.

Entities:  

Keywords:  Ectogenesis; Genetics; Health care allocation; IVF; PGD; Reproduction

Mesh:

Year:  2017        PMID: 28155097     DOI: 10.1007/s11948-017-9875-5

Source DB:  PubMed          Journal:  Sci Eng Ethics        ISSN: 1353-3452            Impact factor:   3.525


  12 in total

1.  Assisted reproduction policies in Israel: a retrospective analysis of in vitro fertilization-embryo transfer.

Authors:  Frida Simonstein; Michal Mashiach-Eizenberg; Ariel Revel; Johnny S Younis
Journal:  Fertil Steril       Date:  2014-08-20       Impact factor: 7.329

2.  Scientific research is a moral duty.

Authors:  John Harris
Journal:  J Med Ethics       Date:  2005-04       Impact factor: 2.903

3.  The artificial womb: a pilot study considering people's views on the artificial womb and ectogenesis in Israel.

Authors:  Frida Simonstein; Michal Mashiach-Eizenberg
Journal:  Camb Q Healthc Ethics       Date:  2009       Impact factor: 1.284

4.  Commentary: the emergence and application of active aging in Europe.

Authors:  Alan Walker
Journal:  J Aging Soc Policy       Date:  2009 Jan-Mar

5.  Embryonic stem cells: the disagreement debate and embryonic stem cell research in Israel.

Authors:  F Simonstein
Journal:  J Med Ethics       Date:  2008-10       Impact factor: 2.903

6.  Genome engineering using the CRISPR-Cas9 system.

Authors:  F Ann Ran; Patrick D Hsu; Jason Wright; Vineeta Agarwala; David A Scott; Feng Zhang
Journal:  Nat Protoc       Date:  2013-10-24       Impact factor: 13.491

Review 7.  The moral obligation to create children with the best chance of the best life.

Authors:  Julian Savulescu; Guy Kahane
Journal:  Bioethics       Date:  2009-06       Impact factor: 1.898

8.  Biotechnology. A prudent path forward for genomic engineering and germline gene modification.

Authors:  David Baltimore; Paul Berg; Michael Botchan; Dana Carroll; R Alta Charo; George Church; Jacob E Corn; George Q Daley; Jennifer A Doudna; Marsha Fenner; Henry T Greely; Martin Jinek; G Steven Martin; Edward Penhoet; Jennifer Puck; Samuel H Sternberg; Jonathan S Weissman; Keith R Yamamoto
Journal:  Science       Date:  2015-03-19       Impact factor: 47.728

9.  Eliminate mitochondrial diseases by gene editing in germ-line cells and embryos.

Authors:  Si Wang; Fei Yi; Jing Qu
Journal:  Protein Cell       Date:  2015-07       Impact factor: 14.870

10.  The moral imperative to continue gene editing research on human embryos.

Authors:  Julian Savulescu; Jonathan Pugh; Thomas Douglas; Christopher Gyngell
Journal:  Protein Cell       Date:  2015-07       Impact factor: 14.870

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