Hong-Fei Tong1, Hong-Bo Liang2, Zhi-Kang Mo2, Tian-Pei Guan2, Jian Yang2, Chi-Hua Fang3. 1. Department of Hepatobiliary Surgery, ZhuJiang Hospital of Southern Medical University, Guangzhou, Guangdong Province 510282, China. Electronic address: tonghongfei@sina.com. 2. Department of Hepatobiliary Surgery, ZhuJiang Hospital of Southern Medical University, Guangzhou, Guangdong Province 510282, China. 3. Department of Hepatobiliary Surgery, ZhuJiang Hospital of Southern Medical University, Guangzhou, Guangdong Province 510282, China. Electronic address: fangch_dr@163.com.
Abstract
OBJECTIVE: To confirm the histological grade of hepatocellular carcinoma (HCC) by gadoxetic acid-enhanced MRI. METHODS: Ninety-five HCC patients underwent gadoxetic acid-enhanced MRI before surgical intervention. The correlations among the signal absolute enhancement, contrast enhancement ratio (CER) and tumor histological grade were analyzed. RESULTS: The correlation between CER of tumor-to-liver and the grades of tumor differentiation is the most significant negative. The k-value for the CER of tumor-to-liver and histopathologic analysis is 0.62, which gives evidence of good agreement. CONCLUSION: The quantitative analysis of gadoxetic acid-enhanced MRI can predict the histological grades of small HCCs.
OBJECTIVE: To confirm the histological grade of hepatocellular carcinoma (HCC) by gadoxetic acid-enhanced MRI. METHODS: Ninety-five HCCpatients underwent gadoxetic acid-enhanced MRI before surgical intervention. The correlations among the signal absolute enhancement, contrast enhancement ratio (CER) and tumor histological grade were analyzed. RESULTS: The correlation between CER of tumor-to-liver and the grades of tumor differentiation is the most significant negative. The k-value for the CER of tumor-to-liver and histopathologic analysis is 0.62, which gives evidence of good agreement. CONCLUSION: The quantitative analysis of gadoxetic acid-enhanced MRI can predict the histological grades of small HCCs.