Literature DB >> 28153391

Plant-Made Vaccines in the Fight Against Cancer.

Alejandra Wong-Arce1, Omar González-Ortega2, Sergio Rosales-Mendoza3.   

Abstract

Immunotherapies constitute an important trend in developing new cancer treatments, and several promising candidates are under evaluation in clinical trials. Plants have entered the fight against cancer because they constitute low-cost and efficient hosts for biopharmaceutical production that can also serve as oral delivery vehicles. This review is focused on the knowledge gained through the development of anticancer plant-made vaccines reported thus far, and highlights the potential of this technology - its success being reflected in the number of candidates that are close to market. Future prospects for anticancer plant-made vaccines are also identified. Copyright Â
© 2016 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  anti-idiotype antibodies; immunotherapies; malignances; parenteral delivery; subunit vaccines; tumor-associated antigen

Mesh:

Substances:

Year:  2017        PMID: 28153391     DOI: 10.1016/j.tibtech.2016.12.002

Source DB:  PubMed          Journal:  Trends Biotechnol        ISSN: 0167-7799            Impact factor:   19.536


  5 in total

1.  Alfalfa mosaic virus nanoparticles-based in situ vaccination induces antitumor immune responses in breast cancer model.

Authors:  Mehdi Shahgolzari; Maghsoud Pazhouhandeh; Morteza Milani; Steven Fiering; Ahmad Yari Khosroushahi
Journal:  Nanomedicine (Lond)       Date:  2021-01-14       Impact factor: 5.307

2.  High-level expression of the HIV entry inhibitor griffithsin from the plastid genome and retention of biological activity in dried tobacco leaves.

Authors:  Matthijs Hoelscher; Nadine Tiller; Audrey Y-H Teh; Guo-Zhang Wu; Julian K-C Ma; Ralph Bock
Journal:  Plant Mol Biol       Date:  2018-06-09       Impact factor: 4.076

3.  Sanguinarine exhibits potent efficacy against cervical cancer cells through inhibiting the STAT3 pathway in vitro and in vivo.

Authors:  Huijuan Zhang; Jing Zhang; Puja S Venkat; Chenglei Gu; Yuanguang Meng
Journal:  Cancer Manag Res       Date:  2019-08-14       Impact factor: 3.989

Review 4.  Expression of Single Chain Variable Fragment (scFv) Molecules in Plants: A Comprehensive Update.

Authors:  Padikara Kutty Satheeshkumar
Journal:  Mol Biotechnol       Date:  2020-03       Impact factor: 2.695

5.  Effect of leaf position and days post-infiltration on transient expression of colorectal cancer vaccine candidate proteins GA733-Fc and GA733-FcK in Nicotiana benthamiana plant.

Authors:  Kibum Kim; Yang Joo Kang; Se Ra Park; Do-Sun Kim; Seung-Won Lee; Kinarm Ko; Daniel Ponndorf; Kisung Ko
Journal:  PeerJ       Date:  2021-04-07       Impact factor: 2.984

  5 in total

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