| Literature DB >> 28151640 |
Maddalena Bertolla1, Lucia Cenci2, Andrea Anesi1, Emmanuele Ambrosi3, Franco Tagliaro4, Lia Vanzetti5, Graziano Guella1, Alessandra Maria Bossi2.
Abstract
Molecular imprinted poly(acrylamido)-derivative nanogels have shown their selectivity to bind the protein human serum transferrin (HTR) and also showed their capability for instantaneous solvent-induced modification upon the addition of acetonitrile. Integrated to matrix-assisted laser desorption/ionization time-of-flight mass analysis the HTR-imprinted solvent-responsive nanogels permitted the determination of HTR straight from serum and offered novel perspectives in targeted protein analysis.Entities:
Keywords: MALDI; mass spectrometry; molecularly imprinted polymers; nanogels; polyacrylamide; responsive material; serum transferrin; targeted protein analysis
Mesh:
Substances:
Year: 2017 PMID: 28151640 DOI: 10.1021/acsami.6b16291
Source DB: PubMed Journal: ACS Appl Mater Interfaces ISSN: 1944-8244 Impact factor: 9.229