Literature DB >> 28149870

Targeting colorectal cancer (stem-like) cells using LGR5 directed antibody drug conjugates.

Daniela Hirsch1, Thomas Ried2.   

Abstract

Entities:  

Year:  2016        PMID: 28149870      PMCID: PMC5233515          DOI: 10.21037/atm.2016.11.78

Source DB:  PubMed          Journal:  Ann Transl Med        ISSN: 2305-5839


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  25 in total

Review 1.  Lgr5 and Lgr6 as markers to study adult stem cell roles in self-renewal and cancer.

Authors:  M Leushacke; N Barker
Journal:  Oncogene       Date:  2011-10-17       Impact factor: 9.867

2.  Bmi1 is expressed in vivo in intestinal stem cells.

Authors:  Eugenio Sangiorgi; Mario R Capecchi
Journal:  Nat Genet       Date:  2008-06-08       Impact factor: 38.330

3.  Lgr5(+ve) stem/progenitor cells contribute to nephron formation during kidney development.

Authors:  Nick Barker; Maarten B Rookmaaker; Pekka Kujala; Annie Ng; Marc Leushacke; Hugo Snippert; Marc van de Wetering; Shawna Tan; Johan H Van Es; Meritxell Huch; Richard Poulsom; Marianne C Verhaar; Peter J Peters; Hans Clevers
Journal:  Cell Rep       Date:  2012-09-20       Impact factor: 9.423

4.  Overexpression of leucine-rich repeat-containing G protein-coupled receptor 5 in colorectal cancer.

Authors:  Hiroshi Uchida; Ken Yamazaki; Mariko Fukuma; Taketo Yamada; Tetsu Hayashida; Hirotoshi Hasegawa; Masaki Kitajima; Yuko Kitagawa; Michiie Sakamoto
Journal:  Cancer Sci       Date:  2010-03-24       Impact factor: 6.716

5.  A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable.

Authors:  Hua Tian; Brian Biehs; Søren Warming; Kevin G Leong; Linda Rangell; Ophir D Klein; Frederic J de Sauvage
Journal:  Nature       Date:  2011-09-18       Impact factor: 49.962

6.  In situ validation of an intestinal stem cell signature in colorectal cancer.

Authors:  Jennifer L Ziskin; Debra Dunlap; Murat Yaylaoglu; Imola K Fodor; William F Forrest; Rajesh Patel; Nianfeng Ge; Gordon G Hutchins; James K Pine; Philip Quirke; Hartmut Koeppen; Adrian M Jubb
Journal:  Gut       Date:  2012-05-25       Impact factor: 23.059

7.  Lgr5 marks stem/progenitor cells in ovary and tubal epithelia.

Authors:  Annie Ng; Shawna Tan; Gurmit Singh; Pamela Rizk; Yada Swathi; Tuan Zea Tan; Ruby Yun-Ju Huang; Marc Leushacke; Nick Barker
Journal:  Nat Cell Biol       Date:  2014-07-06       Impact factor: 28.824

8.  In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration.

Authors:  Meritxell Huch; Craig Dorrell; Sylvia F Boj; Johan H van Es; Vivian S W Li; Marc van de Wetering; Toshiro Sato; Karien Hamer; Nobuo Sasaki; Milton J Finegold; Annelise Haft; Robert G Vries; Markus Grompe; Hans Clevers
Journal:  Nature       Date:  2013-01-27       Impact factor: 49.962

9.  Lineage tracing reveals Lgr5+ stem cell activity in mouse intestinal adenomas.

Authors:  Arnout G Schepers; Hugo J Snippert; Daniel E Stange; Maaike van den Born; Johan H van Es; Marc van de Wetering; Hans Clevers
Journal:  Science       Date:  2012-08-01       Impact factor: 47.728

10.  Identification of stem cells in small intestine and colon by marker gene Lgr5.

Authors:  Nick Barker; Johan H van Es; Jeroen Kuipers; Pekka Kujala; Maaike van den Born; Miranda Cozijnsen; Andrea Haegebarth; Jeroen Korving; Harry Begthel; Peter J Peters; Hans Clevers
Journal:  Nature       Date:  2007-10-14       Impact factor: 49.962

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  2 in total

1.  Identification, isolation and characterization of human LGR5-positive colon adenoma cells.

Authors:  Michael K Dame; Durga Attili; Shannon D McClintock; Priya H Dedhia; Peter Ouillette; Olaf Hardt; Alana M Chin; Xiang Xue; Julie Laliberte; Erica L Katz; Gina M Newsome; David R Hill; Alyssa J Miller; Yu-Hwai Tsai; David Agorku; Christopher H Altheim; Andreas Bosio; Becky Simon; Linda C Samuelson; Jay A Stoerker; Henry D Appelman; James Varani; Max S Wicha; Dean E Brenner; Yatrik M Shah; Jason R Spence; Justin A Colacino
Journal:  Development       Date:  2018-03-14       Impact factor: 6.862

2.  Salinomycin exerts anti-colorectal cancer activity by targeting the β-catenin/T-cell factor complex.

Authors:  Zhongyuan Wang; Liang Zhou; Yanpeng Xiong; Shubin Yu; Huan Li; Jiaoyang Fan; Fan Li; Zijie Su; Jiaxing Song; Qi Sun; Shan-Shan Liu; Yuqing Xia; Liang Zhao; Shiyue Li; Fang Guo; Peng Huang; Dennis A Carson; Desheng Lu
Journal:  Br J Pharmacol       Date:  2019-07-24       Impact factor: 8.739

  2 in total

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