| Literature DB >> 28149571 |
Martin Schweiger1, Walter Knirsch2, Niko Cesarovic3, Bernard Krüger4, Martin Schmiady1, Thomas Frauenfelder5, Laura Frese6, Hitendu Dave1, Simon Philipp Hoerstrup6, Michael Hübler1.
Abstract
To overcome current limitations of valve substitutes and tissue substitutes the technology of tissue engineering (TE) continues to offer new perspectives in congenital cardiac surgery. We report our experiences and results implanting a decellularized TE patch in nine sheep in orthotropic position as aortic valve leaflet substitute. Establishing the animal model, feasibility, cardiopulmonary bypass issues and operative technique are highlighted.Entities:
Keywords: Tissue engineering; aortic valve; cardiac surgical procedures; models, animal
Year: 2016 PMID: 28149571 PMCID: PMC5227253 DOI: 10.21037/jtd.2016.12.72
Source DB: PubMed Journal: J Thorac Dis ISSN: 2072-1439 Impact factor: 2.895