BACKGROUND: Bullectomy using autosutures is the standard procedure in patients with primary spontaneous pneumothorax (PSP). However, postoperative bulla neogenesis (POBN) along the staple line is relatively common and promotes PSP recurrence. We have previously reported the relationship between POBN and resected lung weight (LW). However, recently published data indicate that young patients with PSP have a high postoperative recurrence rate. Therefore, we evaluated the relationship between POBN and LW in PSP patients, subdivided according to age. METHODS: Between February 2011 and April 2016, 96 lung-resection sites in 67 patients who underwent bullectomy were evaluated. Patients were subdivided into two groups by age: Y group (<25 years, 56 sites) and O group (≥25 years, 40 sites). We used the inverse-probability of treatment weighted (IPTW) method to adjust for the heterogeneity in their backgrounds. POBN was diagnosed by computed tomography. RESULTS: Cox regression analysis for the O group indicated that LW ≥3.0 g was a significant risk factor for POBN (P=0.049). For the Y group, no association between lung weight and POBN was observed. CONCLUSIONS: A LW ≥3.0 g is a significant risk factor for POBN in individuals aged ≥25 years.
BACKGROUND: Bullectomy using autosutures is the standard procedure in patients with primary spontaneous pneumothorax (PSP). However, postoperative bulla neogenesis (POBN) along the staple line is relatively common and promotes PSP recurrence. We have previously reported the relationship between POBN and resected lung weight (LW). However, recently published data indicate that young patients with PSP have a high postoperative recurrence rate. Therefore, we evaluated the relationship between POBN and LW in PSPpatients, subdivided according to age. METHODS: Between February 2011 and April 2016, 96 lung-resection sites in 67 patients who underwent bullectomy were evaluated. Patients were subdivided into two groups by age: Y group (<25 years, 56 sites) and O group (≥25 years, 40 sites). We used the inverse-probability of treatment weighted (IPTW) method to adjust for the heterogeneity in their backgrounds. POBN was diagnosed by computed tomography. RESULTS: Cox regression analysis for the O group indicated that LW ≥3.0 g was a significant risk factor for POBN (P=0.049). For the Y group, no association between lung weight and POBN was observed. CONCLUSIONS: A LW ≥3.0 g is a significant risk factor for POBN in individuals aged ≥25 years.
Authors: Saswata Deb; Peter C Austin; Jack V Tu; Dennis T Ko; C David Mazer; Alex Kiss; Stephen E Fremes Journal: Can J Cardiol Date: 2015-05-23 Impact factor: 5.223
Authors: Si Young Choi; Young Du Kim; Do Yeon Kim; Jong Hui Suh; Jeong Seob Yoon; Yeo Rok Kim; Eun Kyung Yu; Chan Beom Park Journal: J Thorac Dis Date: 2018-03 Impact factor: 2.895
Authors: Si Young Choi; Do Yeon Kim; Jong Hui Suh; Jeong Seob Yoon; Jin Yong Jeong; Chan Beom Park Journal: J Thorac Dis Date: 2018-07 Impact factor: 2.895