Nikita Vasudeva1, Prem Singh Nirwan2, Preeti Shrivastava2. 1. Department of Microbiology, NIMS UNIVERSITY Shobha Nagar, Jaipur-Delhi Highway (NH-11C), Jaipur - 303121, Jaipur, Rajasthan, India. 2. National Institute of Medical Sciences & Research, NIMS University, Jaipur, India.
Abstract
BACKGROUND: Invasion of the bloodstream by microorganisms constitutes one of the most serious situations in infectious disease. Microorganisms present in circulating blood whether continuously, intermittently, or transiently are a threat to every organ in the body. Prevalence and antimicrobial susceptibility of microorganisms vary depending upon the geography and the use of antibiotics. METHODS: A cross-sectional study to determine the prevalent organisms causing bloodstream infection was conducted. BACTEC BD 9050 system was used to identify the causative organism, and sub-cultures were done on MacConkey Agar and Blood Agar. Antibiotic susceptibility test (AST) was done using Kirby B Disk diffusion method. RESULTS: A total of 170 patients were enrolled, and blood samples of 53 patients showed growth of organisms. Staphylococcus aureus was the most commonly isolated organism. Most of the Gram-positive cocci (GPC) were susceptible to vancomycin and linezolid. Most of the Gram-negative bacilli (GNB) showed sensitivity to cefoperazone/sulbactam followed by imipenem.
BACKGROUND: Invasion of the bloodstream by microorganisms constitutes one of the most serious situations in infectious disease. Microorganisms present in circulating blood whether continuously, intermittently, or transiently are a threat to every organ in the body. Prevalence and antimicrobial susceptibility of microorganisms vary depending upon the geography and the use of antibiotics. METHODS: A cross-sectional study to determine the prevalent organisms causing bloodstream infection was conducted. BACTEC BD 9050 system was used to identify the causative organism, and sub-cultures were done on MacConkey Agar and Blood Agar. Antibiotic susceptibility test (AST) was done using Kirby B Disk diffusion method. RESULTS: A total of 170 patients were enrolled, and blood samples of 53 patients showed growth of organisms. Staphylococcus aureus was the most commonly isolated organism. Most of the Gram-positive cocci (GPC) were susceptible to vancomycin and linezolid. Most of the Gram-negative bacilli (GNB) showed sensitivity to cefoperazone/sulbactam followed by imipenem.
Authors: Alexander M Aiken; Neema Mturi; Patricia Njuguna; Shebe Mohammed; James A Berkley; Isaiah Mwangi; Salim Mwarumba; Barnes S Kitsao; Brett S Lowe; Susan C Morpeth; Andrew J Hall; Iqbal Khandawalla; J Anthony G Scott Journal: Lancet Date: 2011-11-29 Impact factor: 79.321
Authors: James A Karlowsky; Mark E Jones; Deborah C Draghi; Clyde Thornsberry; Daniel F Sahm; Gregory A Volturo Journal: Ann Clin Microbiol Antimicrob Date: 2004-05-10 Impact factor: 3.944