Literature DB >> 28149244

Monitoring and treatment of coagulation abnormalities in burn patients. an international survey on current practices.

A Lavrentieva1, N Depetris2, E Kaimakamis1, M Berardino2, M Stella3.   

Abstract

The magnitude of coagulation abnormalities, and the definition and treatment of coagulopathy in burn patients are inadequately understood and continue to be discussed in the literature. We aimed to analyse physicians' views on monitoring and treating coagulation abnormalities in burn patients. A total of 350 questionnaires were distributed electronically to burn ICU physicians. Participation was voluntary and anonymous. Responses were analysed electronically and comparisons were made according to the region of the ICU or the specialty of the physician. Of the 350 questionnaires distributed, 55 (15.7%) were returned. The majority of burn specialists consider sepsis-induced coagulopathy to be the most frequent coagulopathy in burn patients, and 74.5% declare that they do not use any specific definition/scoring system in their department to detect coagulopathy. The majority of specialists (70.8%) use standard coagulation tests. The most frequent indications for plasma transfusion are massive bleeding (32.8%) and Disseminated Intravascular Coagulation syndrome treatment (20%). The main specific factors reported in our study are cryoprecipitate (23.2%) and fibrinogen concentrate (18.9%). 21.1% of respondents state that they do not use any specific coagulation factor substitution in burn patients. Specific coagulation factor substitution is not a routine practice. The low response rate precludes the generalization of our results.

Entities:  

Keywords:  blood coagulation; burn; monitoring; treatment

Year:  2016        PMID: 28149244      PMCID: PMC5266232     

Source DB:  PubMed          Journal:  Ann Burns Fire Disasters        ISSN: 1592-9558


  26 in total

1.  Towards definition, clinical and laboratory criteria, and a scoring system for disseminated intravascular coagulation.

Authors:  F B Taylor; C H Toh; W K Hoots; H Wada; M Levi
Journal:  Thromb Haemost       Date:  2001-11       Impact factor: 5.249

2.  A high fresh frozen plasma: packed red blood cell transfusion ratio decreases mortality in all massively transfused trauma patients regardless of admission international normalized ratio.

Authors:  Lisa M Brown; Seppo O Aro; Mitchell J Cohen; J B Holcomb; C E Wade; K J Brasel; G Vercruysse; J MacLeod; R P Dutton; J R Hess; J C Duchesne; N E McSwain; P Muskat; J Johannigamn; H M Cryer; A Tillou; J F Pittet; P Knudson; M A De Moya; M A Schreiber; B Tieu; S Brundage; L M Napolitano; M Brunsvold; K C Sihler; G Beilman; A B Peitzman; M S Zenait; J Sperry; L Alarcon; M A Croce; J P Minei; R Kozar; E A Gonzalez; R M Stewart; S M Cohn; J E Mickalek; E M Bulger; B A Cotton; T C Nunez; R Ivatury; J W Meredith; P Miller; G J Pomper; B Marin
Journal:  J Trauma       Date:  2011-08

3.  Trauma-Induced Coagulopathy.

Authors:  Jeffrey W Simmons; Jean-Francois Pittet; Bert Pierce
Journal:  Curr Anesthesiol Rep       Date:  2014-09-01

4.  Extravascular fibrinogen degradation in experimental burn wounds: a source of fibrin split products.

Authors:  P W Curreri; D L Rayfield; M Vaught; C R Baxter
Journal:  Surgery       Date:  1975-01       Impact factor: 3.982

Review 5.  Disseminated intravascular coagulation in burn injury.

Authors:  Giuseppe Lippi; Luigi Ippolito; Gianfranco Cervellin
Journal:  Semin Thromb Hemost       Date:  2010-07-07       Impact factor: 4.180

6.  The effect of burn wound size on hemostasis: a correlation of the hemostatic changes to the clinical state.

Authors:  A Kowal-Vern; R L Gamelli; J M Walenga; D Hoppensteadt; M Sharp-Pucci; H R Schumacher
Journal:  J Trauma       Date:  1992-07

7.  Recombinant FVIIa decreases perioperative blood transfusion requirement in burn patients undergoing excision and skin grafting--results of a single centre pilot study.

Authors:  Pär Ingemar Johansson; Kirsten Eriksen; Søren Loumann Nielsen; Rasmus Rojkjaer; Bjarne Alsbjørn
Journal:  Burns       Date:  2007-03-26       Impact factor: 2.744

8.  The exclusive use of coagulation factor concentrates enables reversal of coagulopathy and decreases transfusion rates in patients with major blunt trauma.

Authors:  Petra Innerhofer; Isabella Westermann; Helmuth Tauber; Robert Breitkopf; Dietmar Fries; Tobias Kastenberger; Rene El Attal; Alexander Strasak; Markus Mittermayr
Journal:  Injury       Date:  2012-09-20       Impact factor: 2.586

9.  The ratio of blood products transfused affects mortality in patients receiving massive transfusions at a combat support hospital.

Authors:  Matthew A Borgman; Philip C Spinella; Jeremy G Perkins; Kurt W Grathwohl; Thomas Repine; Alec C Beekley; James Sebesta; Donald Jenkins; Charles E Wade; John B Holcomb
Journal:  J Trauma       Date:  2007-10

10.  Interventional Algorithms for the Control of Coagulopathic Bleeding in Surgical, Trauma, and Postpartum Settings: Recommendations From the Share Network Group.

Authors:  Manuela Carvalho; Anabela Rodrigues; Manuela Gomes; Alexandre Carrilho; António Robalo Nunes; Rosário Orfão; Ângela Alves; José Aguiar; Manuel Campos
Journal:  Clin Appl Thromb Hemost       Date:  2014-11-25       Impact factor: 2.389

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  3 in total

1.  Management of pain, anxiety, agitation and delirium in burn patients: a survey of clinical practice and a review of the current literature.

Authors:  N Depetris; S Raineri; O Pantet; A Lavrentieva
Journal:  Ann Burns Fire Disasters       Date:  2018-06-30

Review 2.  Burn-Induced Coagulopathies: a Comprehensive Review.

Authors:  Robert L Ball; John W Keyloun; Kathleen Brummel-Ziedins; Thomas Orfeo; Tina L Palmieri; Laura S Johnson; Lauren T Moffatt; Anthony E Pusateri; Jeffrey W Shupp
Journal:  Shock       Date:  2020-08       Impact factor: 3.533

3.  Cats with thermal burn injuries from California wildfires show echocardiographic evidence of myocardial thickening and intracardiac thrombi.

Authors:  Ashley N Sharpe; Catherine T Gunther-Harrington; Steven E Epstein; Ronald H L Li; Joshua A Stern
Journal:  Sci Rep       Date:  2020-02-14       Impact factor: 4.379

  3 in total

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