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Literature DB >> 28148932

Neurodegenerative disease: Pituitary adenylate cyclase activator ameliorates SBMA.

Sarah Crunkhorn.

Abstract

Entities: Disease Gene

Mesh：

Substances：

Year: 2017 PMID： 28148932 DOI： 10.1038/nrd.2017.11

Source DB: PubMed Journal: Nat Rev Drug Discov ISSN： 1474-1776 Impact factor: 84.694

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1 in total

1. Adenylyl cyclase activating polypeptide reduces phosphorylation and toxicity of the polyglutamine-expanded androgen receptor in spinobulbar muscular atrophy.

Authors: Maria Josè Polanco; Sara Parodi; Diana Piol; Conor Stack; Mathilde Chivet; Andrea Contestabile; Helen C Miranda; Patricia M-J Lievens; Stefano Espinoza; Tobias Jochum; Anna Rocchi; Christopher Grunseich; Raul R Gainetdinov; Andrew C B Cato; Andrew P Lieberman; Albert R La Spada; Fabio Sambataro; Kenneth H Fischbeck; Illana Gozes; Maria Pennuto
Journal: Sci Transl Med Date: 2016-12-21 Impact factor: 17.956

1 in total