| Literature DB >> 28148291 |
Javaid Alam1, Fazal Subhan2, Ihsan Ullah3, Muhammad Shahid1, Gowhar Ali1, Robert D E Sewell4.
Abstract
Entities:
Year: 2017 PMID: 28148291 PMCID: PMC5288848 DOI: 10.1186/s40360-017-0117-x
Source DB: PubMed Journal: BMC Pharmacol Toxicol ISSN: 2050-6511 Impact factor: 2.483
Percent of DPPH free radical scavenging activity and antioxidant strength of N-(2-mercaptopropionyl) glycine (MPG), vitamin C (Vit- C), grape seed proanthocyanidin (GP), B. monnieri n-butanolic fraction (BM-ButFr) or standard butylated hydroxytoluene (BHT) against their respective concentrations
| Concentration (μg/mL) | Percent inhibition (%) | ||||
|---|---|---|---|---|---|
| BHT | MPG | Vit-C | GP | BM-ButFr | |
| 1 | 15.0 ± 0.7 | 20.0 ± 2.1 | 14.6 ± 1.5 | 36.4 ± 0.8 | 24.5 ± 0.7 |
| 10 | 24.4 ± 4.2 | 20.8 ± 1.8 | 15.7 ± 0.6 | 71.6 ± 0.7 | 20.9 ± 0.8 |
| 30 | 22.1 ± 1.4 | 19.4 ± 1.2 | 17.3 ± 1.5 | 82.6 ± 1.2 | 32.2 ± 2.4 |
| 50 | 22.8 ± 0.5 | 24.4 ± 1.0 | 21.2 ± 2.4 | 92.4 ± 0.1 | 46.5 ± 2.9 |
| 100 | 58.6 ± 3.8 | 94.0 ± 0.01 | 92.7 ± 0.7 | 92.4 ± 0.2 | 90.9 ± 0.5 |
| 200 | 89.7 ± 2.4 | 96.2 ± 0.2 | 96.0 ± 0.3 | 91.6 ± 0.3 | 90.7 ± 0.3 |
| 500 | 93.8 ± 0.1 | 96.0 ± 0.7 | 96.7 ± 0.2 | 89.6 ± 0.2 | 89.9 ± 0.4 |
| Antioxidant strength | |||||
| EC50 (μg/mL) | 98.17 ± 3.842 | 67.66 ± 3.095 | 69.42 ± 3.027 | 6.498 ± 0.630 | 55.61 ± 1.137 |
| Antiradical power | 0.0102 ± 0.0004 | 0.0148 ± 0.0007 | 0.0143 ± 0.0005 | 0.1567 ± 0.0145 | 0.0159 ± 0.0010 |
| Stoichiometry | 196.3 ± 7.685 | 135.3 ± 6.191 | 138.8 ± 6.053 | 13.00 ± 1.261 | 111.2 ± 2.274 |
Values are expressed as mean ± S.E.M from three separate experiments