Literature DB >> 28146551

Correction: Normal Levels of Sox9 Expression in the Developing Mouse Testis Depend on the TES/TESCO Enhancer, but This Does Not Act Alone.

Nitzan Gonen, Alexander Quinn, Helen C O'Neill, Peter Koopman, Robin Lovell-Badge.   

Abstract

[This corrects the article DOI: 10.1371/journal.pgen.1006520.].

Entities:  

Year:  2017        PMID: 28146551      PMCID: PMC5287446          DOI: 10.1371/journal.pgen.1006584

Source DB:  PubMed          Journal:  PLoS Genet        ISSN: 1553-7390            Impact factor:   5.917


Errors were introduced during the production process resulting in the incorrect labelling of the genotypes in Fig 5C. Please view the correct Fig 5 here.
Fig 5

Immunofluorescence and real-time quantitative RT-PCR analysis of mice carrying TES deletion on Sox8-null background.

(A) Immunostaining of 14.5 dpc XY testis of wild type and TES-/- embryos on a Sox8-null background. (B) Immunostaining of 8 week-old XY testes of wild type and TES-/- mice on a Sox8-null background. Testes were stained for SOX9 (green), FOXL2 (red) and DAPI (blue). (C) Gene expression in XY TES deleted gonads with Sox8-null background at 14.5 dpc. Data are presented as mean 2-ΔΔCt values normalized to Hprt. Sample size represents number of individuals and is indicated below each genotype. Error bars show SEM of 2-ΔΔCt values. P value is presented above the relevant bars (unpaired, two-tailed t-test on 2-ΔΔCt values). Dark grey bars: XY; light grey bars: XX.

Immunofluorescence and real-time quantitative RT-PCR analysis of mice carrying TES deletion on Sox8-null background.

(A) Immunostaining of 14.5 dpc XY testis of wild type and TES-/- embryos on a Sox8-null background. (B) Immunostaining of 8 week-old XY testes of wild type and TES-/- mice on a Sox8-null background. Testes were stained for SOX9 (green), FOXL2 (red) and DAPI (blue). (C) Gene expression in XY TES deleted gonads with Sox8-null background at 14.5 dpc. Data are presented as mean 2-ΔΔCt values normalized to Hprt. Sample size represents number of individuals and is indicated below each genotype. Error bars show SEM of 2-ΔΔCt values. P value is presented above the relevant bars (unpaired, two-tailed t-test on 2-ΔΔCt values). Dark grey bars: XY; light grey bars: XX.
  1 in total

1.  Normal Levels of Sox9 Expression in the Developing Mouse Testis Depend on the TES/TESCO Enhancer, but This Does Not Act Alone.

Authors:  Nitzan Gonen; Alexander Quinn; Helen C O'Neill; Peter Koopman; Robin Lovell-Badge
Journal:  PLoS Genet       Date:  2017-01-03       Impact factor: 5.917

  1 in total
  1 in total

Review 1.  Cis-Regulatory Control of Mammalian Sex Determination.

Authors:  Meshi Ridnik; Stefan Schoenfelder; Nitzan Gonen
Journal:  Sex Dev       Date:  2021-10-28       Impact factor: 1.824

  1 in total

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