Literature DB >> 28145752

Toward Harnessing Sex Steroid Signaling as a Therapeutic Target in Pulmonary Arterial Hypertension.

Tim Lahm1,2, Andrea L Frump1.   

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Year:  2017        PMID： 28145752      PMCID： PMC5328184          DOI： 10.1164/rccm.201609-1906ED

Source DB:  PubMed          Journal:  Am J Respir Crit Care Med        ISSN： 1073-449X            Impact factor:   21.405


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  15 in total

Review 1.  Right ventricular function in cardiovascular disease, part I: Anatomy, physiology, aging, and functional assessment of the right ventricle.

Authors:  François Haddad; Sharon A Hunt; David N Rosenthal; Daniel J Murphy
Journal:  Circulation       Date:  2008-03-18       Impact factor: 29.690

2.  Estrogen Metabolite 16α-Hydroxyestrone Exacerbates Bone Morphogenetic Protein Receptor Type II-Associated Pulmonary Arterial Hypertension Through MicroRNA-29-Mediated Modulation of Cellular Metabolism.

Authors:  Xinping Chen; Megha Talati; Joshua P Fessel; Anna R Hemnes; Santhi Gladson; Jaketa French; Sheila Shay; Aaron Trammell; John A Phillips; Rizwan Hamid; Joy D Cogan; Elliott P Dawson; Kristie E Womble; Lora K Hedges; Elizabeth G Martinez; Lisa A Wheeler; James E Loyd; Susan J Majka; James West; Eric D Austin
Journal:  Circulation       Date:  2015-10-20       Impact factor: 29.690

3.  Direct and indirect protection of right ventricular function by estrogen in an experimental model of pulmonary arterial hypertension.

Authors:  Aiping Liu; David Schreier; Lian Tian; Jens C Eickhoff; Zhijie Wang; Timothy A Hacker; Naomi C Chesler
Journal:  Am J Physiol Heart Circ Physiol       Date:  2014-06-06       Impact factor: 4.733

4.  Survival in patients with idiopathic, familial, and anorexigen-associated pulmonary arterial hypertension in the modern management era.

Authors:  Marc Humbert; Olivier Sitbon; Ari Chaouat; Michèle Bertocchi; Gilbert Habib; Virginie Gressin; Azzedine Yaïci; Emmanuel Weitzenblum; Jean-François Cordier; François Chabot; Claire Dromer; Christophe Pison; Martine Reynaud-Gaubert; Alain Haloun; Marcel Laurent; Eric Hachulla; Vincent Cottin; Bruno Degano; Xavier Jaïs; David Montani; Rogério Souza; Gérald Simonneau
Journal:  Circulation       Date:  2010-06-28       Impact factor: 29.690

5.  Sex hormones are associated with right ventricular structure and function: The MESA-right ventricle study.

Authors:  Corey E Ventetuolo; Pamela Ouyang; David A Bluemke; Harikrishna Tandri; R Graham Barr; Emilia Bagiella; Anne R Cappola; Michael R Bristow; Craig Johnson; Richard A Kronmal; Jorge R Kizer; Joao A C Lima; Steven M Kawut
Journal:  Am J Respir Crit Care Med       Date:  2010-10-01       Impact factor: 21.405

Review 6.  Progress in solving the sex hormone paradox in pulmonary hypertension.

Authors:  Tim Lahm; Rubin M Tuder; Irina Petrache
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2014-05-09       Impact factor: 5.464

7.  Alterations in oestrogen metabolism: implications for higher penetrance of familial pulmonary arterial hypertension in females.

Authors:  E D Austin; J D Cogan; J D West; L K Hedges; R Hamid; E P Dawson; L A Wheeler; F F Parl; J E Loyd; J A Phillips
Journal:  Eur Respir J       Date:  2009-04-08       Impact factor: 16.671

8.  Anastrozole in Pulmonary Arterial Hypertension. A Randomized, Double-Blind, Placebo-controlled Trial.

Authors:  Steven M Kawut; Christine L Archer-Chicko; Angela DeMichele; Jason S Fritz; James R Klinger; Bonnie Ky; Harold I Palevsky; Amy J Palmisciano; Mamta Patel; Diane Pinder; Kathleen J Propert; K Akaya Smith; Frank Stanczyk; Russell Tracy; Anjali Vaidya; Mary E Whittenhall; Corey E Ventetuolo
Journal:  Am J Respir Crit Care Med       Date:  2017-02-01       Impact factor: 21.405

9.  Anticoagulation and survival in pulmonary arterial hypertension: results from the Comparative, Prospective Registry of Newly Initiated Therapies for Pulmonary Hypertension (COMPERA).

Authors:  Karen M Olsson; Marion Delcroix; H Ardeschir Ghofrani; Henning Tiede; Doerte Huscher; Rudolf Speich; Ekkehard Grünig; Gerd Staehler; Stephan Rosenkranz; Michael Halank; Matthias Held; Tobias J Lange; Juergen Behr; Hans Klose; Martin Claussen; Ralf Ewert; Christian F Opitz; C Dario Vizza; Laura Scelsi; Anton Vonk-Noordegraaf; Harald Kaemmerer; J Simon R Gibbs; Gerry Coghlan; Joanna Pepke-Zaba; Uwe Schulz; Matthias Gorenflo; David Pittrow; Marius M Hoeper
Journal:  Circulation       Date:  2013-09-30       Impact factor: 29.690

10.  Activity of the estrogen-metabolizing enzyme cytochrome P450 1B1 influences the development of pulmonary arterial hypertension.

Authors:  Kevin White; Anne Katrine Johansen; Margaret Nilsen; Loredana Ciuclan; Emma Wallace; Leigh Paton; Annabel Campbell; Ian Morecroft; Lynn Loughlin; John D McClure; Matthew Thomas; Kirsty M Mair; Margaret R MacLean
Journal:  Circulation       Date:  2012-08-02       Impact factor: 29.690
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  4 in total

1.  The Y Chromosome Takes the Field to Modify BMPR2 Expression.

Authors:  Andrea L Frump; Tim Lahm
Journal:  Am J Respir Crit Care Med       Date:  2018-12-15       Impact factor: 21.405

2.  Sex and Gender Differences in Lung Disease.

Authors:  Patricia Silveyra; Nathalie Fuentes; Daniel Enrique Rodriguez Bauza
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

3.  17β-Estradiol and estrogen receptor α protect right ventricular function in pulmonary hypertension via BMPR2 and apelin.

Authors:  Andrea L Frump; Marjorie Albrecht; Bakhtiyor Yakubov; Sandra Breuils-Bonnet; Valérie Nadeau; Eve Tremblay; Francois Potus; Junichi Omura; Todd Cook; Amanda Fisher; Brooke Rodriguez; R Dale Brown; Kurt R Stenmark; C Dustin Rubinstein; Kathy Krentz; Diana M Tabima; Rongbo Li; Xin Sun; Naomi C Chesler; Steeve Provencher; Sebastien Bonnet; Tim Lahm
Journal:  J Clin Invest       Date:  2021-03-15       Impact factor: 14.808

4.  Association of premature menopause with incident pulmonary hypertension: A cohort study.

Authors:  Michael C Honigberg; Aniruddh P Patel; Tim Lahm; Malissa J Wood; Jennifer E Ho; Puja Kohli; Pradeep Natarajan
Journal:  PLoS One       Date:  2021-03-10       Impact factor: 3.752
  4 in total

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