Literature DB >> 28144736

[Candida infiltrations in the iris and lens during iritis and situation after sepsis].

D Kuerten1, M Fuest2, B Mazinani2, P Walter2, N Plange2.   

Abstract

Intraocular Candida infections are overall rather rare; nevertheless they are often found as endogenous infections after Candida sepsis and can be sight-threatening. The most common manifestations are either a sole chorioretinitis or an endophthalmitis. Here we report the case of a 35-year-old man developing Candida infiltrations in the lens capsule and behind the iris after corticosteroid treatment of a presumed HLA-B27-positive iritis. The patient suffered from a life-threatening intensive care stay with positive Candida blood cultures earlier after intestinal perforation. With systemic intracameral and topical voriconazole, the infection was successfully treated. In patients with positive blood samples for Candida, topical and systemic corticosteroids should be given with care even months after the last positive blood cultures.

Entities:  

Keywords:  Infiltrates; Iritis; Ocular candidiasis; Ocular mycosis

Mesh:

Substances:

Year:  2018        PMID: 28144736     DOI: 10.1007/s00347-017-0439-5

Source DB:  PubMed          Journal:  Ophthalmologe        ISSN: 0941-293X            Impact factor:   1.059


  7 in total

Review 1.  Treatment of endogenous fungal endophthalmitis: focus on new antifungal agents.

Authors:  James Riddell; Grant M Comer; Carol A Kauffman
Journal:  Clin Infect Dis       Date:  2011-01-16       Impact factor: 9.079

2.  Ocular manifestations of candidemia.

Authors:  Astrid M L Oude Lashof; Aniki Rothova; Jack D Sobel; Markus Ruhnke; Peter G Pappas; Claudio Viscoli; Haran T Schlamm; Iwona T Oborska; John H Rex; Bart Jan Kullberg
Journal:  Clin Infect Dis       Date:  2011-08-01       Impact factor: 9.079

3.  Epidemiology of Candida blood stream infections in patients with hematological malignancies or solid tumors.

Authors:  Janina Zirkel; Hartwig Klinker; Anna Kuhn; Marianne Abele-Horn; Dennis Tappe; Doris Turnwald; Hermann Einsele; Werner J Heinz
Journal:  Med Mycol       Date:  2011-06-22       Impact factor: 4.076

4.  International surveillance of blood stream infections due to Candida species in the European SENTRY Program: species distribution and antifungal susceptibility including the investigational triazole and echinocandin agents. SENTRY Participant Group (Europe).

Authors:  M A Pfaller; R N Jones; G V Doern; A C Fluit; J Verhoef; H S Sader; S A Messer; A Houston; S Coffman; R J Hollis
Journal:  Diagn Microbiol Infect Dis       Date:  1999-09       Impact factor: 2.803

5.  Determination of vitreous, aqueous, and plasma concentration of orally administered voriconazole in humans.

Authors:  Seenu M Hariprasad; William F Mieler; Eric R Holz; Hua Gao; Judy E Kim; Jingduan Chi; Randall A Prince
Journal:  Arch Ophthalmol       Date:  2004-01

6.  Clinical practice guidelines for the management of cryptococcal disease: 2010 update by the infectious diseases society of america.

Authors:  John R Perfect; William E Dismukes; Francoise Dromer; David L Goldman; John R Graybill; Richard J Hamill; Thomas S Harrison; Robert A Larsen; Olivier Lortholary; Minh-Hong Nguyen; Peter G Pappas; William G Powderly; Nina Singh; Jack D Sobel; Tania C Sorrell
Journal:  Clin Infect Dis       Date:  2010-02-01       Impact factor: 9.079

7.  Prevalence and factors predictive of intraocular fungal infection in patients with fungemia at an academic urban tertiary care center.

Authors:  Elena Geraymovych; Joseph H Conduff; Puneet S Braich; Christopher T Leffler; Vikram S Brar
Journal:  Clin Ophthalmol       Date:  2015-09-29
  7 in total

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