Literature DB >> 28144432

Efficacy of Antimicrobial Photodynamic Therapy as an Adjunctive to Mechanical Debridement in the Treatment of Peri-implant Diseases: A Randomized Controlled Clinical Trial.

Mohammad Reza Karimi1, Ali Hasani2, Salva Khosroshahian3.   

Abstract

Introduction: The purpose of the present study was to assess the clinical effects of anti-microbial photodynamic therapy (PDT) after closed surface scaling in the treatment of peri-implant diseases.
Methods: Ten patients with a total of 15 pairs of dental implants, showing clinical and radiographic signs of peri-implant diseases, were included in this study. In each patient, one implant randomly served as control implant and the other served as test implant. The control implants were treated with closed surface scaling only and the test implants received additionally PDT, using light with a wavelength of 630 nm and intensity of 2000 mw/cm2 for 120 seconds after application of photosensitizer in peri-implant sulcus. Clinical parameters were evaluated before and 1.5 and 3 months after treatment.
Results: Statistical analysis showed significant differences in probing pocket depth (PPD), clinical attachment loss (CAL), bleeding on probing (BOP), and gingival index (GI) at each time point between the two groups. There were no statistically significant changes with respect to any of the parameters in the control group. Complete resolution of BOP at 3 months was achieved in 100% of test implants. At 1.5 and 3 months, there were significant differences in the mean probing depth and CAL gain measurements at implants in the test group.
Conclusion: The present study revealed that adjunctive use of PDT following closed surface scaling could lead to clinical improvement of peri-implant diseases. Further studies are necessary to confirm our results.

Entities:  

Keywords:  clinical trial; dental implant; mechanical debridement; peri-implantitis; photodynamic therapy

Year:  2016        PMID: 28144432      PMCID: PMC5262478          DOI: 10.15171/jlms.2016.24

Source DB:  PubMed          Journal:  J Lasers Med Sci        ISSN: 2008-9783


  39 in total

Review 1.  Microbiology and antimicrobial therapy of peri-implantitis.

Authors:  Andrea Mombelli
Journal:  Periodontol 2000       Date:  2002       Impact factor: 7.589

2.  Mechanical non-surgical treatment of peri-implantitis: a single-blinded randomized longitudinal clinical study. II. Microbiological results.

Authors:  G Rutger Persson; Emelie Samuelsson; Christel Lindahl; Stefan Renvert
Journal:  J Clin Periodontol       Date:  2010-06       Impact factor: 8.728

3.  Bacterial colonization immediately after installation on oral titanium implants.

Authors:  Mirjam M Fürst; Giovanni E Salvi; Niklaus P Lang; G Rutger Persson
Journal:  Clin Oral Implants Res       Date:  2007-05-15       Impact factor: 5.977

4.  Efficacy of photodynamic therapy on inflammatory signs and two selected periodontopathogenic species in a beagle dog model.

Authors:  Bernd W Sigusch; Anne Pfitzner; Volker Albrecht; Eike Glockmann
Journal:  J Periodontol       Date:  2005-07       Impact factor: 6.993

5.  Bactericidal effects of different laser wavelengths on periodontopathic germs in photodynamic therapy.

Authors:  You Chan; Chern-Hsiung Lai
Journal:  Lasers Med Sci       Date:  2003       Impact factor: 3.161

6.  Impact of the method of surface debridement and decontamination on the clinical outcome following combined surgical therapy of peri-implantitis: a randomized controlled clinical study.

Authors:  Frank Schwarz; Narja Sahm; Gerhard Iglhaut; Jürgen Becker
Journal:  J Clin Periodontol       Date:  2011-01-11       Impact factor: 8.728

7.  Treatment of ligature-induced peri-implantitis by lethal photosensitization and guided bone regeneration: a preliminary histologic study in dogs.

Authors:  Jamil Awad Shibli; Marilia Compagnoni Martins; Francisco Humberto Nociti; Valdir Gouveia Garcia; Elcio Marcantonio
Journal:  J Periodontol       Date:  2003-03       Impact factor: 6.993

8.  Treatment of peri-implantitis by the Vector system.

Authors:  Eva S Karring; Andreas Stavropoulos; Birgit Ellegaard; Thorkild Karring
Journal:  Clin Oral Implants Res       Date:  2005-06       Impact factor: 5.977

9.  Comparative study between the effects of photodynamic therapy and conventional therapy on microbial reduction in ligature-induced peri-implantitis in dogs.

Authors:  Ricardo R A Hayek; Ney S Araújo; Marco A Gioso; Jonathan Ferreira; Carlos A Baptista-Sobrinho; Aécio M Yamada; Martha S Ribeiro
Journal:  J Periodontol       Date:  2005-08       Impact factor: 6.993

10.  Bacterial adhesion on smooth and rough titanium surfaces after treatment with different instruments.

Authors:  Poliana Mendes Duarte; André Figueiredo Reis; Patrícia Moreira de Freitas; Claudia Ota-Tsuzuki
Journal:  J Periodontol       Date:  2009-11       Impact factor: 6.993

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  4 in total

Review 1.  The Application of Antimicrobial Photodynamic Therapy (aPDT) in the Treatment of Peri-Implantitis.

Authors:  Tianyuan Zhao; Jungyul Song; Yuzhuo Ping; Meihua Li
Journal:  Comput Math Methods Med       Date:  2022-05-12       Impact factor: 2.809

Review 2.  The diode laser as coadyuvant therapy in the non-surgical conventional treatment of peri-implant mucositis: A systematic review and meta-analysis.

Authors:  Rebeca Sánchez-Martos; Andrea Samman; Mattia Priami; Santiago Arias-Herrera
Journal:  J Clin Exp Dent       Date:  2020-12-01

3.  Peripheral giant cell granuloma associated with a dental implant.

Authors:  Rafaela Carriço Porto Baesso; Maria Carolina de Lima Jacy Monteiro Barki; Rebeca de Souza Azevedo; Karla Bianca Fernandes da Costa Fontes; Débora Lima Pereira; Renata Tucci; Fábio Ramôa Pires; Bruna Lavinas Sayed Picciani
Journal:  BMC Oral Health       Date:  2019-12-16       Impact factor: 2.757

Review 4.  Photodynamic Therapy for Peri-Implant Diseases.

Authors:  Betul Rahman; Anirudh Balakrishna Acharya; Ruqaiyyah Siddiqui; Elise Verron; Zahi Badran
Journal:  Antibiotics (Basel)       Date:  2022-07-08
  4 in total

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