Winnie A Mar1, Jonathan H Yu2, Martha Gracia Knuttinen3, Jeanne M Horowitz4, Odile David5, Andrew Wilbur1, Christine O Menias3. 1. 1 Department of Radiology, University of Illinois at Chicago, 1740 W Taylor St, Rm 2483 (MC 931), Chicago, IL 60612. 2. 2 Department of Radiology, University of North Carolina, Chapel Hill, NC. 3. 3 Department of Radiology, Mayo Clinic, Scottsdale, AZ. 4. 4 Department of Radiology, Northwestern Memorial Hospital, Chicago, IL. 5. 5 Department of Pathology, University of Illinois at Chicago, Chicago, IL.
Abstract
OBJECTIVE: Rosai-Dorfman disease (RDD) is an uncommon benign histiocytic disorder. Extranodal involvement occurs in 43% and most commonly involves the head and neck, skin, and bones. We review less common imaging findings outside the head and neck. CONCLUSION: The imaging manifestations of RDD overlap with a variety of neoplastic and nonneoplastic conditions. Confirmation of an RDD diagnosis is based on specific histologic features. Radiologic assessment is used to rule out multifocality on initial workup and to evaluate treatment response.
OBJECTIVE:Rosai-Dorfman disease (RDD) is an uncommon benign histiocytic disorder. Extranodal involvement occurs in 43% and most commonly involves the head and neck, skin, and bones. We review less common imaging findings outside the head and neck. CONCLUSION: The imaging manifestations of RDD overlap with a variety of neoplastic and nonneoplastic conditions. Confirmation of an RDD diagnosis is based on specific histologic features. Radiologic assessment is used to rule out multifocality on initial workup and to evaluate treatment response.
Authors: Yi Li; Emily Sloan; Andrew Bollen; David Solomon; Philip Theodosopoulos; Soonmee Cha Journal: Int J Hematol Oncol Stem Cell Res Date: 2021-10-01