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Literature DB >> 28139652

Lnc-ing ROR1-HER3 and Hippo signalling in metastasis.

Abstract

Long noncoding RNAs (lncRNAs) are increasingly recognized for their role in cancer progression. The previously uncharacterized lncRNA MAYA is now shown to promote bone metastasis by bridging ROR1-HER3 and Hippo-YAP pathways. Neuregulin-induced HER3 phosphorylation by ROR1 recruits a MAYA-containing protein complex to methylate Hippo/MST1 and activate YAP target genes that are essential for bone metastasis.

Entities: Disease Gene

Year: 2017 PMID： 28139652 DOI： 10.1038/ncb3467

Source DB: PubMed Journal: Nat Cell Biol ISSN： 1465-7392 Impact factor: 28.824

14 in total

Review 1. ERBB receptors: from oncogene discovery to basic science to mechanism-based cancer therapeutics.

Authors: Carlos L Arteaga; Jeffrey A Engelman
Journal: Cancer Cell Date: 2014-03-17 Impact factor: 31.743

Review 2. The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment.

Authors: Randy Johnson; Georg Halder
Journal: Nat Rev Drug Discov Date: 2013-12-13 Impact factor: 84.694

Review 3. The emerging roles of YAP and TAZ in cancer.

Authors: Toshiro Moroishi; Carsten Gram Hansen; Kun-Liang Guan
Journal: Nat Rev Cancer Date: 2015-01-16 Impact factor: 60.716

4. Regulation of Hippo pathway by mitogenic growth factors via phosphoinositide 3-kinase and phosphoinositide-dependent kinase-1.

Authors: Run Fan; Nam-Gyun Kim; Barry M Gumbiner
Journal: Proc Natl Acad Sci U S A Date: 2013-01-28 Impact factor: 11.205

5. The STAT3-binding long noncoding RNA lnc-DC controls human dendritic cell differentiation.

Authors: Pin Wang; Yiquan Xue; Yanmei Han; Li Lin; Cong Wu; Sheng Xu; Zhengping Jiang; Junfang Xu; Qiuyan Liu; Xuetao Cao
Journal: Science Date: 2014-04-18 Impact factor: 47.728

Review 6. RNA in unexpected places: long non-coding RNA functions in diverse cellular contexts.

Authors: Sarah Geisler; Jeff Coller
Journal: Nat Rev Mol Cell Biol Date: 2013-10-09 Impact factor: 94.444

7. Escape from HER-family tyrosine kinase inhibitor therapy by the kinase-inactive HER3.

Authors: Natalia V Sergina; Megan Rausch; Donghui Wang; Jimmy Blair; Byron Hann; Kevan M Shokat; Mark M Moasser
Journal: Nature Date: 2007-01-07 Impact factor: 49.962

Review 8. ROR1, an embryonic protein with an emerging role in cancer biology.

Authors: Nicholas Borcherding; David Kusner; Guang-Hui Liu; Weizhou Zhang
Journal: Protein Cell Date: 2014-04-22 Impact factor: 14.870

9. A ROR1-HER3-lncRNA signalling axis modulates the Hippo-YAP pathway to regulate bone metastasis.

Authors: Chunlai Li; Shouyu Wang; Zhen Xing; Aifu Lin; Ke Liang; Jian Song; Qingsong Hu; Jun Yao; Zhongyuan Chen; Peter K Park; David H Hawke; Jianwei Zhou; Yan Zhou; Shuxing Zhang; Han Liang; Mien-Chie Hung; Gary E Gallick; Leng Han; Chunru Lin; Liuqing Yang
Journal: Nat Cell Biol Date: 2017-01-23 Impact factor: 28.824

10. Signal integration in TGF-β, WNT, and Hippo pathways.

Authors: Liliana Attisano; Jeffrey L Wrana
Journal: F1000Prime Rep Date: 2013-06-03

16 in total

1. Prognostic value of long non-coding RNA TUG1 in various tumors.

Authors: Na Li; Ke Shi; Xinmei Kang; Wei Li
Journal: Oncotarget Date: 2017-08-07

2. Molecular genetics and targeted therapy of WNT-related human diseases (Review).

Authors: Masuko Katoh; Masaru Katoh
Journal: Int J Mol Med Date: 2017-07-19 Impact factor: 4.101

3. Identification of The Aberrantly Expressed LncRNAs in Hepatocellular Carcinoma: A Bioinformatics Analysis Based on RNA-sequencing.

Authors: Hao-Tian Liao; Ji-Wei Huang; Tian Lan; Jin-Ju Wang; Bo Zhu; Ke-Fei Yuan; Yong Zeng
Journal: Sci Rep Date: 2018-03-29 Impact factor: 4.379

4. Systematic review and meta-analysis of the utility of long non-coding RNA GAS5 as a diagnostic and prognostic cancer biomarker.

Authors: Wei Li; Na Li; Ke Shi; Qiong Chen
Journal: Oncotarget Date: 2017-07-06

5. CircFAT1 sponges miR-375 to promote the expression of Yes-associated protein 1 in osteosarcoma cells.

Authors: Gang Liu; Kangmao Huang; Zhiwei Jie; Yizheng Wu; Junxin Chen; Zizheng Chen; Xiangqian Fang; Shuying Shen
Journal: Mol Cancer Date: 2018-12-04 Impact factor: 27.401

Review 6. Development of Effective Therapeutics Targeting HER3 for Cancer Treatment.

Authors: Xiaolong Liu; Shuang Liu; Hui Lyu; Adam I Riker; Yamin Zhang; Bolin Liu
Journal: Biol Proced Online Date: 2019-03-19 Impact factor: 3.244

Review 7. Understanding the biology of HER3 receptor as a therapeutic target in human cancer.

Authors: Hui Lyu; Amy Han; Erik Polsdofer; Shuang Liu; Bolin Liu
Journal: Acta Pharm Sin B Date: 2018-06-02 Impact factor: 11.413

8. A novel lncRNA PLK4 up-regulated by talazoparib represses hepatocellular carcinoma progression by promoting YAP-mediated cell senescence.

Authors: Yan Jia; Huanhuan Jin; Liyuan Gao; Xiang Yang; Feixia Wang; Hai Ding; Anping Chen; Shanzhong Tan; Feng Zhang; Jiangjuan Shao; Shijun Wang; Shizhong Zheng
Journal: J Cell Mol Med Date: 2020-04-03 Impact factor: 5.310

9. FOXC1-mediated LINC00301 facilitates tumor progression and triggers an immune-suppressing microenvironment in non-small cell lung cancer by regulating the HIF1α pathway.

Authors: Cheng-Cao Sun; Wei Zhu; Shu-Jun Li; Wei Hu; Jian Zhang; Yue Zhuo; Han Zhang; Juan Wang; Yu Zhang; Shao-Xin Huang; Qi-Qiang He; De-Jia Li
Journal: Genome Med Date: 2020-09-02 Impact factor: 11.117

Review 10. Roles for growth factors and mutations in metastatic dissemination.

Authors: Nishanth Belugali Nataraj; Ilaria Marrocco; Yosef Yarden
Journal: Biochem Soc Trans Date: 2021-06-30 Impact factor: 5.407