Literature DB >> 28138859

Utility of Biomarkers in the Management of Inflammatory Bowel Disease.

Gursimran Kochhar1, Bret Lashner2.   

Abstract

OPINION STATEMENT: Inflammatory bowel disease (IBD) is comprised of complex clinical and pathological conditions. It runs a chronic course, and proper management requires constant monitoring of disease activity. Recent evidence suggests that subjective patient scores have a poor correlation with disease activity. Endoscopy remains the gold standard for diagnosing and monitoring disease activity. As healthcare is moving towards less costly and less invasive treatments, the need for biomarkers in the management of IBD is evident. Over the last decade, several biomarkers have been found, which may correct the discrepancy between subjective patient scores and the need for endoscopy.

Entities:  

Keywords:  Biomarkers; Crohn’s disease; Inflammatory bowel disease; Ulcerative colitis

Year:  2017        PMID: 28138859     DOI: 10.1007/s11938-017-0129-z

Source DB:  PubMed          Journal:  Curr Treat Options Gastroenterol        ISSN: 1092-8472


  59 in total

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Journal:  Inflamm Bowel Dis       Date:  2007-12       Impact factor: 5.325

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Journal:  Exp Biol Med (Maywood)       Date:  2004-12

6.  Fecal calprotectin more accurately reflects endoscopic activity of ulcerative colitis than the Lichtiger Index, C-reactive protein, platelets, hemoglobin, and blood leukocytes.

Authors:  Alain M Schoepfer; Christoph Beglinger; Alex Straumann; Ekaterina Safroneeva; Yvonne Romero; David Armstrong; Carsten Schmidt; Michael Trummler; Valérie Pittet; Stephan R Vavricka
Journal:  Inflamm Bowel Dis       Date:  2013-02       Impact factor: 5.325

7.  Clinical trial: vitamin D3 treatment in Crohn's disease - a randomized double-blind placebo-controlled study.

Authors:  S P Jørgensen; J Agnholt; H Glerup; S Lyhne; G E Villadsen; C L Hvas; L E Bartels; J Kelsen; L A Christensen; J F Dahlerup
Journal:  Aliment Pharmacol Ther       Date:  2010-05-11       Impact factor: 8.171

8.  Monocyte-conditioned medium, interleukin-1, and tumor necrosis factor stimulate the acute phase response in human hepatoma cells in vitro.

Authors:  G J Darlington; D R Wilson; L B Lachman
Journal:  J Cell Biol       Date:  1986-09       Impact factor: 10.539

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Journal:  Frontline Gastroenterol       Date:  2010-11-03

10.  The vitamin d receptor and T cell function.

Authors:  Martin Kongsbak; Trine B Levring; Carsten Geisler; Marina Rode von Essen
Journal:  Front Immunol       Date:  2013-06-18       Impact factor: 7.561

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  3 in total

1.  Reduction in Anxiety and Depression Scores Associated with Improvement in Quality of Life in Patients with Inflammatory Bowel Disease.

Authors:  Yasamin Farbod; Jelena Popov; David Armstrong; Smita Halder; John K Marshall; Frances Tse; Maria Ines Pinto-Sanchez; Paul Moayyedi; Usha Chauhan
Journal:  J Can Assoc Gastroenterol       Date:  2021-05-19

2.  Development and Validation of Machine Learning Models in Prediction of Remission in Patients With Moderate to Severe Crohn Disease.

Authors:  Akbar K Waljee; Beth I Wallace; Shirley Cohen-Mekelburg; Yumu Liu; Boang Liu; Kay Sauder; Ryan W Stidham; Ji Zhu; Peter D R Higgins
Journal:  JAMA Netw Open       Date:  2019-05-03

Review 3.  Proteomics and Lipidomics in Inflammatory Bowel Disease Research: From Mechanistic Insights to Biomarker Identification.

Authors:  Bjoern Titz; Raffaella M Gadaleta; Giuseppe Lo Sasso; Ashraf Elamin; Kim Ekroos; Nikolai V Ivanov; Manuel C Peitsch; Julia Hoeng
Journal:  Int J Mol Sci       Date:  2018-09-15       Impact factor: 5.923

  3 in total

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