Literature DB >> 28137904

Bilateral thigh methicillin-resistant Staphylococcus aureus necrotising fasciitis in a man with newly diagnosed Human Immunodeficiency Virus (HIV).

Dhruv Chaudhary1, Amith Subhash1, Juan Galvis2, Juan Guardiola2.   

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) necrotising fasciitis (NF) is rare and constitutes a medical and surgical emergency. We report a case of a 53-year-old man with type-2 diabetes mellitus and newly diagnosed HIV infection who presented with 1 week of progressively worsening bilateral sharp thigh pain. On presentation, he was febrile, tachycardic and had bilateral thigh erythema and mild tenderness without open wounds. He had leucocytosis, lactic acidosis and acute kidney injury. Urgent incision and drainage (I&D) was performed for suspected NF. Blood cultures and I&D were positive for MRSA. Biopsy of bilateral thighs showed NF. He was treated with wound washout and 6 weeks of intravenous antibiotics. After undergoing skin graft for wounds, he was discharged to physical rehabilitation. Here we report severe sepsis from bilateral thigh MRSA NF in a patient with newly diagnosed HIV. 2017 BMJ Publishing Group Ltd.

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Year:  2017        PMID: 28137904      PMCID: PMC5293956          DOI: 10.1136/bcr-2016-218468

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  21 in total

Review 1.  Necrotizing fasciitis.

Authors:  Taro Shimizu; Yasuharu Tokuda
Journal:  Intern Med       Date:  2010-06-15       Impact factor: 1.271

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3.  Hyperbaric oxygen treatment and survival from necrotizing soft tissue infection.

Authors:  David Wilkinson; David Doolette
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Review 4.  Necrotizing fasciitis: current concepts and review of the literature.

Authors:  Babak Sarani; Michelle Strong; Jose Pascual; C William Schwab
Journal:  J Am Coll Surg       Date:  2008-12-12       Impact factor: 6.113

Review 5.  Necrotizing soft-tissue infection: diagnosis and management.

Authors:  Daniel A Anaya; E Patchen Dellinger
Journal:  Clin Infect Dis       Date:  2007-01-22       Impact factor: 9.079

6.  Necrotizing fasciitis caused by community-associated methicillin-resistant Staphylococcus aureus in Los Angeles.

Authors:  Loren G Miller; Francoise Perdreau-Remington; Gunter Rieg; Sheherbano Mehdi; Josh Perlroth; Arnold S Bayer; Angela W Tang; Tieu O Phung; Brad Spellberg
Journal:  N Engl J Med       Date:  2005-04-07       Impact factor: 91.245

7.  Predictors of mortality and limb loss in necrotizing soft tissue infections.

Authors:  Daniel A Anaya; Kerry McMahon; Avery B Nathens; Stephen R Sullivan; Hugh Foy; Eileen Bulger
Journal:  Arch Surg       Date:  2005-02

8.  Clinical relevance of the LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) score for assessment of early necrotizing fasciitis.

Authors:  Chin-Ho Wong; Lay-Wai Khin
Journal:  Crit Care Med       Date:  2005-07       Impact factor: 7.598

Review 9.  Necrotizing fasciitis in rheumatic diseases.

Authors:  M Y Mok; S Y Wong; T M Chan; W M Tang; W S Wong; C S Lau
Journal:  Lupus       Date:  2006       Impact factor: 2.911

10.  The LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) score: a tool for distinguishing necrotizing fasciitis from other soft tissue infections.

Authors:  Chin-Ho Wong; Lay-Wai Khin; Kien-Seng Heng; Kok-Chai Tan; Cheng-Ooi Low
Journal:  Crit Care Med       Date:  2004-07       Impact factor: 7.598

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