Literature DB >> 28137228

An Overview of Currently Available Antimalarials.

Nikolay Yu Gorobets1, Yuriy V Sedash1,2, Brajendra K Singh3, Brijesh Rathi4,5.   

Abstract

BACKGROUND: Despite the substantial progress over the time, malaria remains a major public health concern and causing hundreds of thousands of deaths. Resistance to the available antimalarial therapy increases threat to the global public health.
OBJECTIVE: Overview of currently available antimalarials.
METHOD: Literary survey.
RESULTS: The summarized data about different types of antimalarial therapies and their efficiency and modes of action.
CONCLUSION: Despite the seemingly large number of the drugs currently available for malaria treatment, this arsenal is limited due to the narrow variation of their mechanism of action. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Entities:  

Keywords:  Antimalarial drugs; Antimalarial therapy; Drug resistance; Malaria; Mechanism of action; Plasmodium

Mesh：

Substances：

Year:  2017        PMID： 28137228     DOI： 10.2174/1568026617666170130123520

Source DB:  PubMed          Journal:  Curr Top Med Chem        ISSN： 1568-0266            Impact factor:   3.295


  2 in total

1.  Multistage antiplasmodial activity of hydroxyethylamine compounds, in vitro and in vivo evaluations.

Authors:  Neha Sharma; Yash Gupta; Meenakshi Bansal; Snigdha Singh; Prateek Pathak; Mohd Shahbaaz; Raman Mathur; Jyoti Singh; Mohammad Kashif; Maria Grishina; Vladimir Potemkin; Vinoth Rajendran; Prakasha Kempaiah; Agam Prasad Singh; Brijesh Rathi
Journal:  RSC Adv       Date:  2020-09-25       Impact factor: 4.036

2.  QSAR-Based Virtual Screening: Advances and Applications in Drug Discovery.

Authors:  Bruno J Neves; Rodolpho C Braga; Cleber C Melo-Filho; José Teófilo Moreira-Filho; Eugene N Muratov; Carolina Horta Andrade
Journal:  Front Pharmacol       Date:  2018-11-13       Impact factor: 5.810
  2 in total

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