Literature DB >> 28134450

Lactate Detection in Tumor Cell Cultures Using Organic Transistor Circuits.

Marcel Braendlein1, Anna-Maria Pappa1, Marc Ferro1, Alexia Lopresti2, Claire Acquaviva2, Emilie Mamessier2, George G Malliaras1, Róisín M Owens1.   

Abstract

A biosensing platform based on an organic transistor circuit for metabolite detection in highly complex biological media is introduced. The sensor circuit provides inherent background subtraction allowing for highly specific, sensitive lactate detection in tumor cell cultures. The proposed sensing platform paves the way toward rapid, label-free, and cost-effective clinically relevant in vitro diagnostic tools.
© 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  Warburg effect; Wheatstone bridge circuit; organic electrochemical transistor; poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate); tumor cell cultures

Mesh：

Substances：

Year:  2017        PMID： 28134450     DOI： 10.1002/adma.201605744

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  16 in total

Review 1.  Recent advances in bioelectronics chemistry.

Authors:  Yin Fang; Lingyuan Meng; Aleksander Prominski; Erik N Schaumann; Matthew Seebald; Bozhi Tian
Journal:  Chem Soc Rev       Date:  2020-07-16       Impact factor: 54.564

2.  Transparent, conformable, active multielectrode array using organic electrochemical transistors.

Authors:  Wonryung Lee; Dongmin Kim; Naoji Matsuhisa; Masae Nagase; Masaki Sekino; George G Malliaras; Tomoyuki Yokota; Takao Someya
Journal:  Proc Natl Acad Sci U S A       Date:  2017-09-18       Impact factor: 11.205

Review 3.  Molecular Design Strategies toward Improvement of Charge Injection and Ionic Conduction in Organic Mixed Ionic-Electronic Conductors for Organic Electrochemical Transistors.

Authors:  Nadzeya A Kukhta; Adam Marks; Christine K Luscombe
Journal:  Chem Rev       Date:  2021-12-13       Impact factor: 60.622

4.  A flexible and highly sensitive organic electrochemical transistor-based biosensor for continuous and wireless nitric oxide detection.

Authors:  Yuping Deng; Hui Qi; Yuan Ma; Shangbin Liu; Mingyou Zhao; Zhenhu Guo; Yongsheng Jie; Rui Zheng; Jinzhu Jing; Kuntao Chen; He Ding; Guoqing Lv; Kaiyuan Zhang; Rongfeng Li; Huanyu Cheng; Lingyun Zhao; Xing Sheng; Milin Zhang; Lan Yin
Journal:  Proc Natl Acad Sci U S A       Date:  2022-08-16       Impact factor: 12.779

Review 5.  In Vitro Models for Studying Respiratory Host-Pathogen Interactions.

Authors:  Sarah L Barron; Janire Saez; Róisín M Owens
Journal:  Adv Biol (Weinh)       Date:  2021-05-04

6.  Direct metabolite detection with an n-type accumulation mode organic electrochemical transistor.

Authors:  Anna Maria Pappa; David Ohayon; Alexander Giovannitti; Iuliana Petruta Maria; Achilleas Savva; Ilke Uguz; Jonathan Rivnay; Iain McCulloch; Róisín M Owens; Sahika Inal
Journal:  Sci Adv       Date:  2018-06-22       Impact factor: 14.136

Review 7.  Transistors for Chemical Monitoring of Living Cells.

Authors:  Benoît Piro; Giorgio Mattana; Steeve Reisberg
Journal:  Biosensors (Basel)       Date:  2018-07-04

8.  Layered Double Hydroxide-Modified Organic Electrochemical Transistor for Glucose and Lactate Biosensing.

Authors:  Isacco Gualandi; Marta Tessarolo; Federica Mariani; Danilo Arcangeli; Luca Possanzini; Domenica Tonelli; Beatrice Fraboni; Erika Scavetta
Journal:  Sensors (Basel)       Date:  2020-06-18       Impact factor: 3.576

9.  A DNA-mediated crosslinking strategy to enhance cellular delivery and sensor performance of protein spherical nucleic acids.

Authors:  Jing Yan; Ya-Ling Tan; Min-Jie Lin; Hang Xing; Jian-Hui Jiang
Journal:  Chem Sci       Date:  2020-12-08       Impact factor: 9.825

10.  Organic transistor platform with integrated microfluidics for in-line multi-parametric in vitro cell monitoring.

Authors:  Vincenzo F Curto; Bastien Marchiori; Adel Hama; Anna-Maria Pappa; Magali P Ferro; Marcel Braendlein; Jonathan Rivnay; Michel Fiocchi; George G Malliaras; Marc Ramuz; Róisín M Owens
Journal:  Microsyst Nanoeng       Date:  2017-08-14       Impact factor: 7.127
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