Literature DB >> 28134449

Engineered Multifunctional Nanomedicine for Simultaneous Stereotactic Chemotherapy and Inhibited Osteolysis in an Orthotopic Model of Bone Metastasis.

Chunyan Li1, Yejun Zhang1, Guangcun Chen1, Feng Hu1, Kui Zhao2, Qiangbin Wang1.   

Abstract

A novel multifunctional Ag2 S quantum dot (QD)-based nanomedicine of alendronate (Ald)/doxorubicin (DOX)@Ag2 S is developed for highly effective bone tumor therapy in an orthotopic model. The bone-targeting and osteolysis inhibition of Ald and the chemotherapeutic effect of DOX on the bone tumor are in situ visualized by Ag2 S QDs with emission in the second near-infrared window.
© 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  bone metastasis; molecular imaging; osteolysis inhibition; targeted drug delivery; tumor chemotherapy

Mesh：

Substances：

Year:  2017        PMID： 28134449     DOI： 10.1002/adma.201605754

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  16 in total

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Review 2.  Pro-inflammatory Cytokines and Osteocytes.

Authors:  Miao Zhou; Shuyi Li; Janak L Pathak
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3.  Biomaterials for Orthopaedic Diagnostics and Theranostics.

Authors:  Marian A Ackun-Farmmer; Clyde T Overby; Brittany E Haws; Regine Choe; Danielle S W Benoit
Journal:  Curr Opin Biomed Eng       Date:  2021-06-08

4.  Tuning Ligand Density To Optimize Pharmacokinetics of Targeted Nanoparticles for Dual Protection against Tumor-Induced Bone Destruction.

Authors:  Joseph Vanderburgh; Jordan L Hill; Mukesh K Gupta; Kristin A Kwakwa; Sean K Wang; Kathleen Moyer; Sean K Bedingfield; Alyssa R Merkel; Richard d'Arcy; Scott A Guelcher; Julie A Rhoades; Craig L Duvall
Journal:  ACS Nano       Date:  2020-01-08       Impact factor: 15.881

Review 5.  Recent Progress in the Development of Poly(lactic-co-glycolic acid)-Based Nanostructures for Cancer Imaging and Therapy.

Authors:  Ki-Taek Kim; Jae-Young Lee; Dae-Duk Kim; In-Soo Yoon; Hyun-Jong Cho
Journal:  Pharmaceutics       Date:  2019-06-14       Impact factor: 6.321

6.  Rationally designed pure-inorganic upconversion nanoprobes for ultra-highly selective hydrogen sulfide imaging and elimination in vivo.

Authors:  Yuxin Liu; Qi Jia; Xuejiao Zhai; Fang Mao; Anqi Jiang; Jing Zhou
Journal:  Chem Sci       Date:  2018-11-12       Impact factor: 9.825

7.  Size-transformable antigen-presenting cell-mimicking nanovesicles potentiate effective cancer immunotherapy.

Authors:  Weijing Yang; Hongzhang Deng; Shoujun Zhu; Joseph Lau; Rui Tian; Sheng Wang; Zijian Zhou; Guocan Yu; Lang Rao; Liangcan He; Ying Ma; Xiaoyuan Chen
Journal:  Sci Adv       Date:  2020-12-11       Impact factor: 14.136

8.  Molecular imaging of Toll-like receptor 4 detects ischemia-reperfusion injury during intussusception.

Authors:  Zhang-Chun Hu; Ya-Lan Tan; Shun-Gen Huang; Peng Pan; Xiao-Bo Liu; Jian Wang; Wan-Liang Guo
Journal:  Oncotarget       Date:  2017-12-22

9.  Mechanically-Loaded Breast Cancer Cells Modify Osteocyte Mechanosensitivity by Secreting Factors That Increase Osteocyte Dendrite Formation and Downstream Resorption.

Authors:  Wenbo Wang; Blayne A Sarazin; Gabriel Kornilowicz; Maureen E Lynch
Journal:  Front Endocrinol (Lausanne)       Date:  2018-07-03       Impact factor: 5.555

Review 10.  The optimized drug delivery systems of treating cancer bone metastatic osteolysis with nanomaterials.

Authors:  Xi Cheng; Jinrong Wei; Qi Ge; Danlei Xing; Xuefeng Zhou; Yunzhu Qian; Guoqin Jiang
Journal:  Drug Deliv       Date:  2021-12       Impact factor: 6.819
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