| Literature DB >> 2813263 |
K H Rosler1, J Wright, K M Fox, R M Waters, P S Callery.
Abstract
Proton NMR spectroscopy was applied to the assignment of the isomeric identity of commercially available chlorprothixene. Nuclear Overhauser effect studies confirmed that the clinically useful isomer is the cis (Z) configuration. An NMR method for determining the isomeric content of chlorprothixene was developed based on integration of the ratio of areas of signal strength of the cis-N-methyl in comparison to the trans-N-methyl resonances.Entities:
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Year: 1989 PMID： 2813263 DOI： 10.1023/a:1015942623581
Source DB: PubMed Journal: Pharm Res ISSN： 0724-8741 Impact factor: 4.200