Chikara Ueki1, Hiroaki Miyata2, Noboru Motomura2, Genichi Sakaguchi3, Takehide Akimoto3, Shinichi Takamoto2. 1. Department of Cardiovascular Surgery, Shizuoka General Hospital, Shizuoka, Japan; Japan Cardiovascular Surgery Database Organization, Tokyo, Japan. Electronic address: uekichikara@gmail.com. 2. Japan Cardiovascular Surgery Database Organization, Tokyo, Japan. 3. Department of Cardiovascular Surgery, Shizuoka General Hospital, Shizuoka, Japan; Japan Cardiovascular Surgery Database Organization, Tokyo, Japan.
Abstract
BACKGROUND: Adverse effects of previous percutaneous coronary intervention (PCI) on clinical outcomes after coronary artery bypass grafting (CABG) are unclear. This study aimed to evaluate the effect of previous PCI on early outcomes after subsequent CABG by using data from the Japanese national database. METHODS: This study analyzed data from 48,051 consecutive patients that were retrieved from the Japan Adult Cardiovascular Surgery Database. These patients underwent primary, isolated, elective CABG between January 2008 and December 2013. Early mortality and morbidity rates in patients with previous PCI (n = 12,457, 25.9%) were compared with those in patients with no PCI (n = 35,594, 74.1%) by using multivariate logistic regression analysis and propensity score analysis. RESULTS: Operative mortality rates (no PCI, 1.2%; previous PCI, 1.2%; P = 0.970) and morbidity rates (no PCI, 7.4%; previous PCI, 7.2%; p = 0.436) were similar between the two groups. In risk-adjusted multivariate logistic-regression analysis, previous PCI (odds ratio [OR], 1.00; 95% confidence interval [CI], 0.82 to 1.22; p = 0.995) and morbidity (OR, 0.97; 95% CI, 0.89 to 1.05; p = 0.391) were not significant risk factors of operative mortality. Inverse probability of treatment weighting using the propensity score confirmed these results. CONCLUSIONS: This study shows that a previous PCI procedure does not increase postoperative adverse events after subsequent CABG. In the setting of repeat coronary revascularization, the most appropriate method of revascularization should be selected by the heart team, without being affected by a history of a previous PCI procedure.
BACKGROUND: Adverse effects of previous percutaneous coronary intervention (PCI) on clinical outcomes after coronary artery bypass grafting (CABG) are unclear. This study aimed to evaluate the effect of previous PCI on early outcomes after subsequent CABG by using data from the Japanese national database. METHODS: This study analyzed data from 48,051 consecutive patients that were retrieved from the Japan Adult Cardiovascular Surgery Database. These patients underwent primary, isolated, elective CABG between January 2008 and December 2013. Early mortality and morbidity rates in patients with previous PCI (n = 12,457, 25.9%) were compared with those in patients with no PCI (n = 35,594, 74.1%) by using multivariate logistic regression analysis and propensity score analysis. RESULTS: Operative mortality rates (no PCI, 1.2%; previous PCI, 1.2%; P = 0.970) and morbidity rates (no PCI, 7.4%; previous PCI, 7.2%; p = 0.436) were similar between the two groups. In risk-adjusted multivariate logistic-regression analysis, previous PCI (odds ratio [OR], 1.00; 95% confidence interval [CI], 0.82 to 1.22; p = 0.995) and morbidity (OR, 0.97; 95% CI, 0.89 to 1.05; p = 0.391) were not significant risk factors of operative mortality. Inverse probability of treatment weighting using the propensity score confirmed these results. CONCLUSIONS: This study shows that a previous PCI procedure does not increase postoperative adverse events after subsequent CABG. In the setting of repeat coronary revascularization, the most appropriate method of revascularization should be selected by the heart team, without being affected by a history of a previous PCI procedure.
Authors: Jose C Nicolau; Susanna R Stevens; Hussein R Al-Khalidi; Fabio B Jatene; Remo H M Furtado; Luis A O Dallan; Luiz A F Lisboa; Patrice Desvigne-Nickens; Haissam Haddad; E Marc Jolicoeur; Mark C Petrie; Torsten Doenst; Robert E Michler; E Magnus Ohman; Jyotsna Maddury; Imtiaz Ali; Marek A Deja; Jean L Rouleau; Eric J Velazquez; James A Hill Journal: Int J Cardiol Date: 2019-03-15 Impact factor: 4.164
Authors: Fausto Biancari; Antonio Salsano; Francesco Santini; Marisa De Feo; Magnus Dalén; Qiyao Zhang; Giuseppe Gatti; Enzo Mazzaro; Ilaria Franzese; Ciro Bancone; Marco Zanobini; Tuomas Tauriainen; Timo Mäkikallio; Matteo Saccocci; Alessandra Francica; Stefano Rosato; Zein El-Dean; Francesco Onorati; Giovanni Mariscalco Journal: J Clin Med Date: 2022-09-28 Impact factor: 4.964