Literature DB >> 28131203

Temporal evolution of the trident and piglet signs of osmotic demyelination syndrome.

Shin C Beh1.   

Abstract

Central pontine myelinolysis (CPM) is a potentially-devastating complication of rapid osmolar shifts, classically attributed to overlyaggressive correction of chronic hyponatremia. Magnetic resonance imaging (MRI) allowed earlier diagnosis of CPM, but most importantly, it has revealed that the odds of good functional recovery are surprisingly high. A trident shaped pontine lesion is a typical finding in CPM (the trident sign). The "piglet sign" is a much less well-known radiologic finding in CPM. Due to the rarity of CPM, very little has been published on the evolution of these MRI findings. We present a case of CPM in an alcoholic young man, and describe the temporal evolution of both the trident and piglet signs on MRI in CPM.
Copyright © 2017 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Ataxia; Central pontine myelinolysis; Hyponatremia; Osmotic demyelination syndrome; Piglet sign; Trident sign

Mesh:

Year:  2017        PMID: 28131203     DOI: 10.1016/j.jns.2017.01.024

Source DB:  PubMed          Journal:  J Neurol Sci        ISSN: 0022-510X            Impact factor:   3.181


  3 in total

Review 1.  Treatment of Severe Hyponatremia.

Authors:  Richard H Sterns
Journal:  Clin J Am Soc Nephrol       Date:  2018-01-02       Impact factor: 8.237

Review 2.  Toxic and metabolic leukoencephalopathies in emergency department patients: a primer for the radiologist.

Authors:  Neal R Shah; Shahrzad Tavana; Akwasi Opoku; Douglas Martin
Journal:  Emerg Radiol       Date:  2022-02-24

3.  A case of chronic asymptomatic central pontine myelinolysis with histological evidence of remyelination.

Authors:  Harry R Haynes; Patrick J Gallagher; Andrea Cordaro; Marcus Likeman; Seth Love
Journal:  Forensic Sci Med Pathol       Date:  2017-11-25       Impact factor: 2.007

  3 in total

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