Literature DB >> 28131134

Novel Therapies for Postmenopausal Osteoporosis.

Leonardo Bandeira1, John P Bilezikian2.   

Abstract

Recently discovered mechanisms have assisted in developing new therapies for osteoporosis. New classes of drugs have been developed for the treatment of postmenopausal osteoporosis. Although there have been numerous advances over the past 2 decades, the search for newer therapies continues.
Copyright © 2016 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Antiresorptive; Osteoanabolic; Osteoporosis; Postmenopausal; Therapeutics

Mesh：

Substances：

Year:  2016        PMID： 28131134     DOI： 10.1016/j.ecl.2016.11.001

Source DB:  PubMed          Journal:  Endocrinol Metab Clin North Am        ISSN： 0889-8529            Impact factor:   4.741


  9 in total

1.  Loss of Gsα in osteocytes leads to osteopenia due to sclerostin induced suppression of osteoblast activity.

Authors:  Keertik Fulzele; Christopher Dedic; Forest Lai; Mary Bouxsein; Sutada Lotinun; Roland Baron; Paola Divieti Pajevic
Journal:  Bone       Date:  2018-09-25       Impact factor: 4.398

2.  Bisphosphonates prevent age-related weight loss in Japanese postmenopausal women.

Authors:  Tomohiko Urano; Masataka Shiraki; Tatsuhiko Kuroda; Shiro Tanaka; Fumihiko Urano; Kazuhiro Uenishi; Satoshi Inoue
Journal:  J Bone Miner Metab       Date:  2017-12-13       Impact factor: 2.626

3.  Progranulin, a moderator of estrogen/estrogen receptor α binding, regulates bone homeostasis through PERK/p-eIF2 signaling pathway.

Authors:  Yuyou Yang; Naibo Feng; Li Liang; Rong Jiang; Yiming Pan; Nana Geng; Mengtian Fan; Xiaoli Li; Fengjin Guo
Journal:  J Mol Med (Berl)       Date:  2022-07-15       Impact factor: 5.606

4.  Cathepsin K inhibition preserves compressive load in lumbar vertebrae of osteoporotic monkeys.

Authors:  Isabel D Colón-Bernal; Le T Duong; Brenda Pennypacker; James Henderson; Kenneth M Kozloff; Mark M Banaszak Holl
Journal:  Bone Rep       Date:  2018-10-18

5.  Development and validation of a gene signature predicting the risk of postmenopausal osteoporosis.

Authors:  Wei Yuan; Maowei Yang; Yue Zhu
Journal:  Bone Joint Res       Date:  2022-08       Impact factor: 4.410

Review 6.  Associations between ERα/β gene polymorphisms and osteoporosis susceptibility and bone mineral density in postmenopausal women: a systematic review and meta-analysis.

Authors:  Heping Zhu; Jiannong Jiang; Qiang Wang; Jun Zong; Liang Zhang; Tieliang Ma; Youjia Xu; Leiyan Zhang
Journal:  BMC Endocr Disord       Date:  2018-02-20       Impact factor: 2.763

Review 7.  Associations between VDR Gene Polymorphisms and Osteoporosis Risk and Bone Mineral Density in Postmenopausal Women: A systematic review and Meta-Analysis.

Authors:  Liang Zhang; Xin Yin; Jingcheng Wang; Daolinag Xu; Yongxiang Wang; Jiandong Yang; Yuping Tao; Shengfei Zhang; Xinmin Feng; Caifeng Yan
Journal:  Sci Rep       Date:  2018-01-17       Impact factor: 4.379

8.  Proanthocyanidin-rich grape seed extract improves bone loss, bone healing, and implant osseointegration in ovariectomized animals.

Authors:  Taichi Tenkumo; Alkebaier Aobulikasimu; Yoshinori Asou; Midori Shirato; Shunichi Shishido; Taro Kanno; Yoshimi Niwano; Keiichi Sasaki; Keisuke Nakamura
Journal:  Sci Rep       Date:  2020-06-01       Impact factor: 4.379

9.  MicroRNA-151a-3p Functions in the Regulation of Osteoclast Differentiation: Significance to Postmenopausal Osteoporosis.

Authors:  Yuehui He; Di Chen; Qian Guo; Pinghua Shi; Conglei You; Yanping Feng
Journal:  Clin Interv Aging       Date:  2021-07-14       Impact factor: 4.458
  9 in total

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