Literature DB >> 28130682

Therapies for Hemorrhagic Transformation in Acute Ischemic Stroke.

Joshua A Stone1, Joshua Z Willey2, Salah Keyrouz3, James Butera4, Ryan A McTaggart5, Shawna Cutting1, Brian Silver1, Bradford Thompson1,6, Karen L Furie1, Shadi Yaghi7.   

Abstract

OPINION STATEMENT: Hemorrhagic transformation occurs in about 10-15% of patients with acute ischemic stroke. The treatment of hemorrhagic conversion is complex and includes blood pressure management, reversing coagulopathy, and managing its complications including increased intracranial pressure. Future research should be directed on identifying indications to treat and use of appropriate homeostatic regimens to effectively reverse the different anticoagulants and thrombolytic agents in an attempt to improve outcomes of patients with hemorrhagic transformation.

Entities:  

Keywords:  Anticoagulation; Hemorrhagic transformation; Ischemic stroke; Thrombolytic therapy; Treatment

Year:  2017        PMID： 28130682     DOI： 10.1007/s11940-017-0438-5

Source DB:  PubMed          Journal:  Curr Treat Options Neurol        ISSN： 1092-8480            Impact factor:   3.598


  99 in total

1.  Treatment of intracerebral hemorrhage with tranexamic acid after thrombolysis with tissue plasminogen activator.

Authors:  K F French; Jacob White; R E Hoesch
Journal:  Neurocrit Care       Date:  2012-08       Impact factor: 3.210

2.  Efficacy and safety of anticoagulant treatment in acute cardioembolic stroke: a meta-analysis of randomized controlled trials.

Authors:  Maurizio Paciaroni; Giancarlo Agnelli; Sara Micheli; Valeria Caso
Journal:  Stroke       Date:  2007-01-04       Impact factor: 7.914

3.  Neutralization of the anticoagulant effects of heparin with protamine (salmine).

Authors:  T W PARKIN; W F KVALE
Journal:  Am Heart J       Date:  1949-03       Impact factor: 4.749

4.  Thromboembolic adverse events after use of recombinant human coagulation factor VIIa.

Authors:  Kathryn A O'Connell; Jennifer J Wood; Robert P Wise; Jay N Lozier; M Miles Braun
Journal:  JAMA       Date:  2006-01-18       Impact factor: 56.272

Review 5.  Bleeding risk and reversal strategies for old and new anticoagulants and antiplatelet agents.

Authors:  M Levi; E Eerenberg; P W Kamphuisen
Journal:  J Thromb Haemost       Date:  2011-09       Impact factor: 5.824

6.  Poor prognosis in warfarin-associated intracranial hemorrhage despite anticoagulation reversal.

Authors:  Dar Dowlatshahi; Kenneth S Butcher; Negar Asdaghi; Susan Nahirniak; Manya L Bernbaum; Antonio Giulivi; Jason K Wasserman; Man-Chiu Poon; Shelagh B Coutts
Journal:  Stroke       Date:  2012-05-03       Impact factor: 7.914

7.  Prothrombin complex concentrate versus standard therapies for INR reversal in trauma patients receiving warfarin.

Authors:  Scott A Chapman; Eric D Irwin; Alan L Beal; Nichole M Kulinski; Katherine E Hutson; Melissa A L Thorson
Journal:  Ann Pharmacother       Date:  2011-07-20       Impact factor: 3.154

8.  Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials.

Authors:  Werner Hacke; Geoffrey Donnan; Cesare Fieschi; Markku Kaste; Rüdiger von Kummer; Joseph P Broderick; Thomas Brott; Michael Frankel; James C Grotta; E Clarke Haley; Thomas Kwiatkowski; Steven R Levine; Chris Lewandowski; Mei Lu; Patrick Lyden; John R Marler; Suresh Patel; Barbara C Tilley; Gregory Albers; Erich Bluhmki; Manfred Wilhelm; Scott Hamilton
Journal:  Lancet       Date:  2004-03-06       Impact factor: 79.321

9.  Efficacy and safety of tissue plasminogen activator 3 to 4.5 hours after acute ischemic stroke: a metaanalysis.

Authors:  Maarten G Lansberg; Erich Bluhmki; Vincent N Thijs
Journal:  Stroke       Date:  2009-05-28       Impact factor: 7.914

10.  Efficacy and safety of a 4-factor prothrombin complex concentrate in patients on vitamin K antagonists presenting with major bleeding: a randomized, plasma-controlled, phase IIIb study.

Authors:  Ravi Sarode; Truman J Milling; Majed A Refaai; Antoinette Mangione; Astrid Schneider; Billie L Durn; Joshua N Goldstein
Journal:  Circulation       Date:  2013-08-09       Impact factor: 29.690
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  10 in total

Review 1.  Activated protein C in neuroprotection and malaria.

Authors:  Laurent O Mosnier
Journal:  Curr Opin Hematol       Date:  2019-09       Impact factor: 3.284

2.  Ability of weakly supervised learning to detect acute ischemic stroke and hemorrhagic infarction lesions with diffusion-weighted imaging.

Authors:  Chen Cao; Zhiyang Liu; Guohua Liu; Song Jin; Shuang Xia
Journal:  Quant Imaging Med Surg       Date:  2022-01

3.  Lower uric acid level may be associated with hemorrhagic transformation after intravenous thrombolysis.

Authors:  Yuxuan Tian; Qianqian Xie; Jiulin You; Shaonan Yang; Hongqin Zhao; Yuqiang Song
Journal:  Neurol Sci       Date:  2021-11-24       Impact factor: 3.830

4.  Predictors of Radiographic and Symptomatic Hemorrhagic Conversion Following Endovascular Thrombectomy for Acute Ischemic Stroke Due to Large Vessel Occlusion.

Authors:  Kainaat Javed; Andre Boyke; Ishan Naidu; Jessica Ryvlin; Rose Fluss; Adisson N Fortunel; Joseph Dardick; Devikarani Kadaba; David J Altschul; Neil Haranhalli
Journal:  Cureus       Date:  2022-04-24

5.  Pinocembrin attenuates hemorrhagic transformation after delayed t-PA treatment in thromboembolic stroke rats by regulating endogenous metabolites.

Authors:  Ling-Lei Kong; Li Gao; Ke-Xin Wang; Nan-Nan Liu; Cheng-di Liu; Guo-Dong Ma; Hai-Guang Yang; Xue-Mei Qin; Guan-Hua Du
Journal:  Acta Pharmacol Sin       Date:  2021-04-15       Impact factor: 7.169

Review 6.  Improving Cerebral Blood Flow after Arterial Recanalization: A Novel Therapeutic Strategy in Stroke.

Authors:  Mohamad El Amki; Susanne Wegener
Journal:  Int J Mol Sci       Date:  2017-12-09       Impact factor: 5.923

7.  High Neutrophil-to-Platelet Ratio Is Associated With Hemorrhagic Transformation in Patients With Acute Ischemic Stroke.

Authors:  Weilei He; Yiting Ruan; Chengxiang Yuan; Qianqian Cheng; Haoran Cheng; Yaying Zeng; Yunbin Chen; Guiqian Huang; Huijun Chen; Jincai He
Journal:  Front Neurol       Date:  2019-12-10       Impact factor: 4.003

8.  Flat Panel CT Scanning Is Helpful in Predicting Hemorrhagic Transformation in Acute Ischemic Stroke Patients Undergoing Endovascular Thrombectomy.

Authors:  Liuwei Chen; Yi Xu; Rui Shen; Jiping Sun; Xiang Zhang; Quanbin Zhang; Feng Wang
Journal:  Biomed Res Int       Date:  2021-04-13       Impact factor: 3.411

Review 9.  Hemorrhagic Transformation After Ischemic Stroke: Mechanisms and Management.

Authors:  Ji Man Hong; Da Sol Kim; Min Kim
Journal:  Front Neurol       Date:  2021-11-30       Impact factor: 4.003

10.  The Hsp90 Inhibitor 17-DMAG Attenuates Hyperglycemia-Enhanced Hemorrhagic Transformation in Experimental Stroke.

Authors:  Jiaming Zhang; Kai Wang; Jia Qi; Xiaodong Cao; Feng Wang
Journal:  Biomed Res Int       Date:  2021-02-02       Impact factor: 3.411
  10 in total

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