Literature DB >> 28130503

Chlorogenic acid from coffee beans: evaluating the evidence for a blood pressure-regulating health claim.

Tara B Loader1,2, Carla G Taylor1,3,2, Peter Zahradka1,3,2, Peter J H Jones1,4.   

Abstract

The consumption of coffee has been associated with a number of health benefits, including a reduced risk of cardiovascular disease. Hypertension is an important risk factor for adverse cardiovascular events. Coffee may help reduce blood pressure (BP) in humans, which might be attributable to its polyphenolic compound, chlorogenic acid. The high incidence of hypertension among Canadians underscores the need for new and effective strategies to reduce BP. Dietary interventions may constitute such a strategy, but consumers need to be informed about which foods are most effective for regulating BP. To guide healthy eating, Health Canada permits the use of health claims on the labels of foods that confer health benefits. Currently, there is only one health claim for BP regulation. Additional health claims for foods that assist in BP regulation are therefore warranted. This review provides background information on chlorogenic acid and examines the evidence regarding the use of chlorogenic acid for BP regulation in the context of Health Canada's health claims framework.
© The Author(s) 2017. Published by Oxford University Press on behalf of the International Life Sciences Institute. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  blood pressure; chlorogenic acid; coffee; health claim; hypertension

Mesh:

Substances:

Year:  2017        PMID: 28130503     DOI: 10.1093/nutrit/nuw057

Source DB:  PubMed          Journal:  Nutr Rev        ISSN: 0029-6643            Impact factor:   7.110


  7 in total

1.  Double-blind controlled dietary cross-over intervention with differentially fertilised intact lettuce leaves shows acute reduction in blood pressure in young adults, associated with faster uptake of nitrate than of phenolics.

Authors:  Mario Siervo; Kirsten Brandt; Othman K Qadir; Chris J Seal; Ammar W Ashor; Michele Tassotti; Pedro Mena; Daniele Del Rio
Journal:  Eur J Nutr       Date:  2022-07-23       Impact factor: 4.865

Review 2.  The effect of green coffee extract supplementation on cardio metabolic risk factors: a systematic review and meta-analysis of randomized controlled trials.

Authors:  Mehrnaz Morvaridi; Elham Rayyani; Malihe Jaafari; Alireza Khiabani; Mehran Rahimlou
Journal:  J Diabetes Metab Disord       Date:  2020-05-15

Review 3.  Cardiovascular protection effect of chlorogenic acid: focus on the molecular mechanism.

Authors:  Mifetika Lukitasari; Mohammad Saifur Rohman; Dwi Adi Nugroho; Nashi Widodo; Nur Ida Panca Nugrahini
Journal:  F1000Res       Date:  2020-12-15

Review 4.  Factors affecting intake, metabolism and health benefits of phenolic acids: do we understand individual variability?

Authors:  Andreia Bento-Silva; Ville M Koistinen; Pedro Mena; Maria R Bronze; Kati Hanhineva; Stefan Sahlstrøm; Vaida Kitrytė; Sofia Moco; Anna-Marja Aura
Journal:  Eur J Nutr       Date:  2019-05-21       Impact factor: 5.614

Review 5.  Antioxidant Food Components for the Prevention and Treatment of Cardiovascular Diseases: Effects, Mechanisms, and Clinical Studies.

Authors:  Dan-Dan Zhou; Min Luo; Ao Shang; Qian-Qian Mao; Bang-Yan Li; Ren-You Gan; Hua-Bin Li
Journal:  Oxid Med Cell Longev       Date:  2021-01-28       Impact factor: 6.543

6.  Effect of Dewaxed Coffee on Gastroesophageal Symptoms in Patients with GERD: A Randomized Pilot Study.

Authors:  Barbara Polese; Luana Izzo; Nicola Mancino; Marcella Pesce; Sara Rurgo; Maria Cristina Tricarico; Sonia Lombardi; Barbara De Conno; Giovanni Sarnelli; Alberto Ritieni
Journal:  Nutrients       Date:  2022-06-16       Impact factor: 6.706

7.  Chlorogenic Acid Targeting of the AKT PH Domain Activates AKT/GSK3β/FOXO1 Signaling and Improves Glucose Metabolism.

Authors:  Jie Gao; Xin He; Yuejiao Ma; Xuezhi Zhao; Xiaotao Hou; Erwei Hao; Jiagang Deng; Gang Bai
Journal:  Nutrients       Date:  2018-09-23       Impact factor: 5.717

  7 in total

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