| Literature DB >> 28130023 |
Shizuo Kayama1, Hiroki Ohge2, Motoyuki Sugai3.
Abstract
Stealth-type carbapenem-resistant Enterobacteriaceae that are resistant to almost all β-lactams except imipenem is emerging in Japan. This resistance is mediated by specific variants of the metallo-β-lactamases (blaIMP-6 or blaIMP-34) that differs by one amino acid from the common variant blaIMP-1. We developed an amplification refractory mutation system (ARMS) PCR assay enabling rapid, sequence independent, identification of these variants.Entities:
Keywords: ARMS-PCR; Metallo-β-lactamase; Stealth-type resistance phenotype; bla(IMP-34); bla(IMP-6)
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Year: 2017 PMID： 28130023 DOI： 10.1016/j.mimet.2017.01.013
Source DB: PubMed Journal: J Microbiol Methods ISSN： 0167-7012 Impact factor: 2.363