Literature DB >> 28129862

Chemical screening in zebrafish for novel biological and therapeutic discovery.

D S Wiley1, S E Redfield1, L I Zon1.   

Abstract

Zebrafish chemical screening allows for an in vivo assessment of small molecule modulation of biological processes. Compound toxicities, chemical alterations by metabolism, pharmacokinetic and pharmacodynamic properties, and modulation of cell niches can be studied with this method. Furthermore, zebrafish screening is straightforward and cost effective. Zebrafish provide an invaluable platform for novel therapeutic discovery through chemical screening.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Chemical; Chemoinformatic; Hit; Libraries; Phenotype; Screen; Zebrafish

Mesh：

Substances：

Year:  2016        PMID： 28129862      PMCID： PMC5535795          DOI： 10.1016/bs.mcb.2016.10.004

Source DB:  PubMed          Journal:  Methods Cell Biol        ISSN： 0091-679X            Impact factor:   1.441


  92 in total

Review 1.  Target-oriented and diversity-oriented organic synthesis in drug discovery.

Authors:  S L Schreiber
Journal:  Science       Date:  2000-03-17       Impact factor: 47.728

2.  Selective small molecule targeting β-catenin function discovered by in vivo chemical genetic screen.

Authors:  Jijun Hao; Ada Ao; Li Zhou; Clare K Murphy; Audrey Y Frist; Jessica J Keel; Curtis A Thorne; Kwangho Kim; Ethan Lee; Charles C Hong
Journal:  Cell Rep       Date:  2013-09-05       Impact factor: 9.423

3.  A zebrafish chemical suppressor screening identifies small molecule inhibitors of the Wnt/β-catenin pathway.

Authors:  Naoyuki Nishiya; Yusuke Oku; Yusuke Kumagai; Yuki Sato; Emi Yamaguchi; Akari Sasaki; Momoko Shoji; Yukimi Ohnishi; Hitoshi Okamoto; Yoshimasa Uehara
Journal:  Chem Biol       Date:  2014-03-27

4.  Three different noggin genes antagonize the activity of bone morphogenetic proteins in the zebrafish embryo.

Authors:  M Fürthauer; B Thisse; C Thisse
Journal:  Dev Biol       Date:  1999-10-01       Impact factor: 3.582

5.  Identification of a new modulator of the intercalated disc in a zebrafish model of arrhythmogenic cardiomyopathy.

Authors:  Angeliki Asimaki; Sudhir Kapoor; Eva Plovie; Anne Karin Arndt; Edward Adams; ZhenZhen Liu; Cynthia A James; Daniel P Judge; Hugh Calkins; Jared Churko; Joseph C Wu; Calum A MacRae; André G Kléber; Jeffrey E Saffitz
Journal:  Sci Transl Med       Date:  2014-06-11       Impact factor: 17.956

6.  Multidimensional in vivo hazard assessment using zebrafish.

Authors:  Lisa Truong; David M Reif; Lindsey St Mary; Mitra C Geier; Hao D Truong; Robert L Tanguay
Journal:  Toxicol Sci       Date:  2013-10-17       Impact factor: 4.849

7.  Automated, quantitative screening assay for antiangiogenic compounds using transgenic zebrafish.

Authors:  T Cameron Tran; Blossom Sneed; Jamil Haider; Delali Blavo; Audrey White; Temitope Aiyejorun; Timothy C Baranowski; Amy L Rubinstein; Thanh N Doan; Raymond Dingledine; Eric M Sandberg
Journal:  Cancer Res       Date:  2007-12-01       Impact factor: 12.701

8.  Identification of Chemical Inhibitors of β-Catenin-Driven Liver Tumorigenesis in Zebrafish.

Authors:  Kimberley J Evason; Macrina T Francisco; Vladislava Juric; Sanjeev Balakrishnan; Maria Del Pilar Lopez Pazmino; John D Gordan; Sanjay Kakar; Jan Spitsbergen; Andrei Goga; Didier Y R Stainier
Journal:  PLoS Genet       Date:  2015-07-02       Impact factor: 5.917

9.  Drug screening in Scn1a zebrafish mutant identifies clemizole as a potential Dravet syndrome treatment.

Authors:  Scott C Baraban; Matthew T Dinday; Gabriela A Hortopan
Journal:  Nat Commun       Date:  2013       Impact factor: 14.919

10.  Selective inhibition of retinal angiogenesis by targeting PI3 kinase.

Authors:  Yolanda Alvarez; Olaya Astudillo; Lasse Jensen; Alison L Reynolds; Nora Waghorne; Derek P Brazil; Yihai Cao; John J O'Connor; Breandán N Kennedy
Journal:  PLoS One       Date:  2009-11-17       Impact factor: 3.240
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  44 in total

1.  Ponatinib-induced cardiotoxicity: delineating the signalling mechanisms and potential rescue strategies.

Authors:  Anand P Singh; Michael S Glennon; Prachi Umbarkar; Manisha Gupte; Cristi L Galindo; Qinkun Zhang; Thomas Force; Jason R Becker; Hind Lal
Journal:  Cardiovasc Res       Date:  2019-04-15       Impact factor: 10.787

Review 2.  Opportunities and challenges for using the zebrafish to study neuronal connectivity as an endpoint of developmental neurotoxicity.

Authors:  Galen W Miller; Vidya Chandrasekaran; Bianca Yaghoobi; Pamela J Lein
Journal:  Neurotoxicology       Date:  2018-04-25       Impact factor: 4.294

3.  Epithelial delamination is protective during pharmaceutical-induced enteropathy.

Authors:  Scott T Espenschied; Mark R Cronan; Molly A Matty; Olaf Mueller; Matthew R Redinbo; David M Tobin; John F Rawls
Journal:  Proc Natl Acad Sci U S A       Date:  2019-08-07       Impact factor: 11.205

Review 4.  Let's get small (and smaller): Combining zebrafish and nanomedicine to advance neuroregenerative therapeutics.

Authors:  David T White; Meera T Saxena; Jeff S Mumm
Journal:  Adv Drug Deliv Rev       Date:  2019-02-12       Impact factor: 15.470

5.  An FDA-Approved Drug Screen for Compounds Influencing Craniofacial Skeletal Development and Craniosynostosis.

Authors:  Marian Seda; Maartje Geerlings; Peggy Lim; Jeshmi Jeyabalan-Srikaran; Ann-Christin Cichon; Peter J Scambler; Philip L Beales; Victor Hernandez-Hernandez; Andrew W Stoker; Dagan Jenkins
Journal:  Mol Syndromol       Date:  2018-07-21

6.  Morphometric analysis and neuroanatomical mapping of the zebrafish brain.

Authors:  Tripti Gupta; Gregory D Marquart; Eric J Horstick; Kathryn M Tabor; Sinisa Pajevic; Harold A Burgess
Journal:  Methods       Date:  2018-06-21       Impact factor: 3.608

Review 7.  Making Waves: New Developments in Toxicology With the Zebrafish.

Authors:  Katharine A Horzmann; Jennifer L Freeman
Journal:  Toxicol Sci       Date:  2018-05-01       Impact factor: 4.849

Review 8.  Use of Zebrafish in Drug Discovery Toxicology.

Authors:  Steven Cassar; Isaac Adatto; Jennifer L Freeman; Joshua T Gamse; Iñaki Iturria; Christian Lawrence; Arantza Muriana; Randall T Peterson; Steven Van Cruchten; Leonard I Zon
Journal:  Chem Res Toxicol       Date:  2019-11-16       Impact factor: 3.739

9.  A nontoxic fungal natural product modulates fin regeneration in zebrafish larvae upstream of FGF-WNT developmental signaling.

Authors:  Paul Cavanah; Junji Itou; Yudi Rusman; Naoyuki Tahara; Jessica M Williams; Christine E Salomon; Yasuhiko Kawakami
Journal:  Dev Dyn       Date:  2020-09-21       Impact factor: 3.780

10.  Drug screening with zebrafish visual behavior identifies carvedilol as a potential treatment for an autosomal dominant form of retinitis pigmentosa.

Authors:  Logan Ganzen; Mee Jung Ko; Mengrui Zhang; Rui Xie; Yongkai Chen; Liyun Zhang; Rebecca James; Jeff Mumm; Richard M van Rijn; Wenxuan Zhong; Chi Pui Pang; Mingzhi Zhang; Motokazu Tsujikawa; Yuk Fai Leung
Journal:  Sci Rep       Date:  2021-06-01       Impact factor: 4.379
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