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Literature DB >> 28129536

A Red Carpet for Iron Metabolism.

Martina U Muckenthaler¹, Stefano Rivella², Matthias W Hentze³, Bruno Galy⁴.

Abstract

200 billion red blood cells (RBCs) are produced every day, requiring more than 2 × 1015 iron atoms every second to maintain adequate erythropoiesis. These numbers translate into 20 mL of blood being produced each day, containing 6 g of hemoglobin and 20 mg of iron. These impressive numbers illustrate why the making and breaking of RBCs is at the heart of iron physiology, providing an ideal context to discuss recent progress in understanding the systemic and cellular mechanisms that underlie the regulation of iron homeostasis and its disorders.

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Year: 2017 PMID： 28129536 PMCID： PMC5706455 DOI： 10.1016/j.cell.2016.12.034

Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582

197 in total

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Journal: Haematologica Date: 2015-04 Impact factor: 9.941

3. Minihepcidins prevent iron overload in a hepcidin-deficient mouse model of severe hemochromatosis.

Authors: Emilio Ramos; Piotr Ruchala; Julia B Goodnough; Léon Kautz; Gloria C Preza; Elizabeta Nemeth; Tomas Ganz
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4. The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis.

Authors: Adriana Donovan; Christine A Lima; Jack L Pinkus; Geraldine S Pinkus; Leonard I Zon; Sylvie Robine; Nancy C Andrews
Journal: Cell Metab Date: 2005-03 Impact factor: 27.287

5. Iron regulatory proteins control a mucosal block to intestinal iron absorption.

Authors: Bruno Galy; Dunja Ferring-Appel; Christiane Becker; Norbert Gretz; Hermann-Josef Gröne; Klaus Schümann; Matthias W Hentze
Journal: Cell Rep Date: 2013-03-21 Impact factor: 9.423

6. A cytosolic iron chaperone that delivers iron to ferritin.

Authors: Haifeng Shi; Krisztina Z Bencze; Timothy L Stemmler; Caroline C Philpott
Journal: Science Date: 2008-05-30 Impact factor: 47.728

7. Lethal Cardiomyopathy in Mice Lacking Transferrin Receptor in the Heart.

Authors: Wenjing Xu; Tomasa Barrientos; Lan Mao; Howard A Rockman; Anthony A Sauve; Nancy C Andrews
Journal: Cell Rep Date: 2015-10-08 Impact factor: 9.423

Review 8. Ironing out Ferroportin.

Authors: Hal Drakesmith; Elizabeta Nemeth; Tomas Ganz
Journal: Cell Metab Date: 2015-10-01 Impact factor: 27.287

Review 9. Hemojuvelin and bone morphogenetic protein (BMP) signaling in iron homeostasis.

Authors: Amanda B Core; Susanna Canali; Jodie L Babitt
Journal: Front Pharmacol Date: 2014-05-13 Impact factor: 5.810

10. A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency.

Authors: Haifa H Jabara; Steven E Boyden; Janet Chou; Narayanaswamy Ramesh; Michel J Massaad; Halli Benson; Wayne Bainter; David Fraulino; Fedik Rahimov; Colin Sieff; Zhi-Jian Liu; Salem H Alshemmari; Basel K Al-Ramadi; Hasan Al-Dhekri; Rand Arnaout; Mohammad Abu-Shukair; Anant Vatsayan; Eli Silver; Sanjay Ahuja; E Graham Davies; Martha Sola-Visner; Toshiro K Ohsumi; Nancy C Andrews; Luigi D Notarangelo; Mark D Fleming; Waleed Al-Herz; Louis M Kunkel; Raif S Geha
Journal: Nat Genet Date: 2015-12-07 Impact factor: 38.330

290 in total

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Authors: Adarsh K Mayank; Vijaya Pandey; Ajay A Vashisht; William D Barshop; Shima Rayatpisheh; Tanu Sharma; Tisha Haque; David N Powers; James A Wohlschlegel
Journal: Mol Cell Date: 2019-06-19 Impact factor: 17.970

2. Enterobactin, an iron chelating bacterial siderophore, arrests cancer cell proliferation.

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Journal: Biochem Pharmacol Date: 2019-06-19 Impact factor: 5.858

Review 3. Crossing the Iron Gate: Why and How Transferrin Receptors Mediate Viral Entry.

Authors: Marianne Wessling-Resnick
Journal: Annu Rev Nutr Date: 2018-05-31 Impact factor: 11.848

Review 4. Liver iron sensing and body iron homeostasis.

Authors: Chia-Yu Wang; Jodie L Babitt
Journal: Blood Date: 2018-11-06 Impact factor: 22.113

Review 5. Iron metabolism under conditions of ineffective erythropoiesis in β-thalassemia.

Authors: Stefano Rivella
Journal: Blood Date: 2018-11-06 Impact factor: 22.113

Review 6. Anemia of inflammation.

Authors: Guenter Weiss; Tomas Ganz; Lawrence T Goodnough
Journal: Blood Date: 2018-11-06 Impact factor: 22.113

10. Fluorescence resonance energy transfer links membrane ferroportin, hephaestin but not ferroportin, amyloid precursor protein complex with iron efflux.

Authors: Adrienne C Dlouhy; Danielle K Bailey; Brittany L Steimle; Haley V Parker; Daniel J Kosman
Journal: J Biol Chem Date: 2019-01-15 Impact factor: 5.157