Literature DB >> 28129105

New Therapeutic Avenue for ALS: Avoiding a Fatal Encounter of TDP-43 at the Mitochondria.

Eloise Hudry1.   

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Year:  2017        PMID： 28129105      PMCID： PMC5363209          DOI： 10.1016/j.ymthe.2016.12.001

Source DB:  PubMed          Journal:  Mol Ther        ISSN： 1525-0016            Impact factor:   11.454


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  16 in total

Review 1.  Emerging targets and treatments in amyotrophic lateral sclerosis.

Authors:  Lorne Zinman; Merit Cudkowicz
Journal:  Lancet Neurol       Date:  2011-05       Impact factor: 44.182

Review 2.  Clinical trials in amyotrophic lateral sclerosis: why so many negative trials and how can trials be improved?

Authors:  Hiroshi Mitsumoto; Benjamin R Brooks; Vincenzo Silani
Journal:  Lancet Neurol       Date:  2014-11       Impact factor: 44.182

3.  Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs.

Authors:  Clotilde Lagier-Tourenne; Magdalini Polymenidou; Kasey R Hutt; Anthony Q Vu; Michael Baughn; Stephanie C Huelga; Kevin M Clutario; Shuo-Chien Ling; Tiffany Y Liang; Curt Mazur; Edward Wancewicz; Aneeza S Kim; Andy Watt; Sue Freier; Geoffrey G Hicks; John Paul Donohue; Lily Shiue; C Frank Bennett; John Ravits; Don W Cleveland; Gene W Yeo
Journal:  Nat Neurosci       Date:  2012-09-30       Impact factor: 24.884

4.  Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.

Authors:  Manuela Neumann; Deepak M Sampathu; Linda K Kwong; Adam C Truax; Matthew C Micsenyi; Thomas T Chou; Jennifer Bruce; Theresa Schuck; Murray Grossman; Christopher M Clark; Leo F McCluskey; Bruce L Miller; Eliezer Masliah; Ian R Mackenzie; Howard Feldman; Wolfgang Feiden; Hans A Kretzschmar; John Q Trojanowski; Virginia M-Y Lee
Journal:  Science       Date:  2006-10-06       Impact factor: 47.728

5.  Motor-Coordinative and Cognitive Dysfunction Caused by Mutant TDP-43 Could Be Reversed by Inhibiting Its Mitochondrial Localization.

Authors:  Wenzhang Wang; Hiroyuki Arakawa; Luwen Wang; Ogoegbunam Okolo; Sandra L Siedlak; Yinfei Jiang; Ju Gao; Fei Xie; Robert B Petersen; Xinglong Wang
Journal:  Mol Ther       Date:  2017-01-04       Impact factor: 11.454

6.  Cytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosis.

Authors:  Sami J Barmada; Gaia Skibinski; Erica Korb; Elizabeth J Rao; Jane Y Wu; Steven Finkbeiner
Journal:  J Neurosci       Date:  2010-01-13       Impact factor: 6.167

7.  Co-morbidity of TDP-43 proteinopathy in Lewy body related diseases.

Authors:  Hanae Nakashima-Yasuda; Kunihiro Uryu; John Robinson; Sharon X Xie; Howard Hurtig; John E Duda; Steven E Arnold; Andrew Siderowf; Murray Grossman; James B Leverenz; Randy Woltjer; Oscar L Lopez; Ronald Hamilton; Debby W Tsuang; Douglas Galasko; Eliezer Masliah; Jeffrey Kaye; Christopher M Clark; Thomas J Montine; Virginia M-Y Lee; John Q Trojanowski
Journal:  Acta Neuropathol       Date:  2007-07-25       Impact factor: 17.088

8.  Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice.

Authors:  Lionel M Igaz; Linda K Kwong; Edward B Lee; Alice Chen-Plotkin; Eric Swanson; Travis Unger; Joe Malunda; Yan Xu; Matthew J Winton; John Q Trojanowski; Virginia M-Y Lee
Journal:  J Clin Invest       Date:  2011-01-04       Impact factor: 14.808

Review 9.  SOD1 and TDP-43 animal models of amyotrophic lateral sclerosis: recent advances in understanding disease toward the development of clinical treatments.

Authors:  Peter I Joyce; Pietro Fratta; Elizabeth M C Fisher; Abraham Acevedo-Arozena
Journal:  Mamm Genome       Date:  2011-06-26       Impact factor: 2.957

10.  The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity.

Authors:  Wenzhang Wang; Luwen Wang; Junjie Lu; Sandra L Siedlak; Hisashi Fujioka; Jingjing Liang; Sirui Jiang; Xiaopin Ma; Zhen Jiang; Edroaldo Lummertz da Rocha; Max Sheng; Heewon Choi; Paul H Lerou; Hu Li; Xinglong Wang
Journal:  Nat Med       Date:  2016-06-27       Impact factor: 53.440
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