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Literature DB >> 28128940

Sequence-Selective Binding of Oligopeptides in Water through Hydrophobic Coding.

Joseph K Awino¹, Roshan W Gunasekara¹, Yan Zhao¹.

Abstract

A general method for sequence-specific binding of peptides remains elusive despite decades of research. By creating an array of "hydrophobically coded dimples" on the surface of surface-core doubly cross-linked micelles, we synthesized water-soluble nanoparticle receptors to recognize peptides by the location, number, and nature of their hydrophobic side chains. Minute differences in the side chains could be distinguished, and affinities up to 20 nM were obtained for biologically active oligopeptides in water.

Entities: Chemical Gene

Mesh：

Substances：
Oligopeptides
Water

Year: 2017 PMID： 28128940 PMCID： PMC5310974 DOI： 10.1021/jacs.6b12949

Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419

23 in total

1. Peptide and protein recognition by designed molecules.

Authors: M W Peczuh; A D Hamilton
Journal: Chem Rev Date: 2000-07-12 Impact factor: 60.622

2. Synthetic hosts via molecular imprinting--are universal synthetic antibodies realistically possible?

Authors: Steven C Zimmerman; N Gabriel Lemcoff
Journal: Chem Commun (Camb) Date: 2003-07-29 Impact factor: 6.222

3. Sequence-dependent stereoselectivity in the binding of tetrapeptides in water by a flexible artificial receptor.

Authors: Carsten Schmuck; Peter Wich
Journal: Angew Chem Int Ed Engl Date: 2006-06-26 Impact factor: 15.336

4. Selective protein capture by epitope imprinting.

Authors: Hidekazu Nishino; Chin-Shiou Huang; Kenneth J Shea
Journal: Angew Chem Int Ed Engl Date: 2006-04-03 Impact factor: 15.336

5. Stereoselective recognition of the Ac-Glu-Tyr-OH dipeptide by pseudopeptidic cages.

Authors: Enrico Faggi; Cristian Vicent; Santiago V Luis; Ignacio Alfonso
Journal: Org Biomol Chem Date: 2015-10-20 Impact factor: 3.876

6. Molecularly imprinted nanoparticles as tailor-made sensors for small fluorescent molecules.

Authors: Joseph K Awino; Yan Zhao
Journal: Chem Commun (Camb) Date: 2014-04-22 Impact factor: 6.222

7. Recognition, neutralization, and clearance of target peptides in the bloodstream of living mice by molecularly imprinted polymer nanoparticles: a plastic antibody.

Authors: Yu Hoshino; Hiroyuki Koide; Takeo Urakami; Hiroaki Kanazawa; Takashi Kodama; Naoto Oku; Kenneth J Shea
Journal: J Am Chem Soc Date: 2010-05-19 Impact factor: 15.419

8. A differential array of metalated synthetic receptors for the analysis of tripeptide mixtures.

Authors: Aaron T Wright; Eric V Anslyn; John T McDevitt
Journal: J Am Chem Soc Date: 2005-12-14 Impact factor: 15.419

9. Factors controlling the complex architecture of native and modified cyclodextrins with dipeptide (Z-Glu-Tyr) studied by microcalorimetry and NMR spectroscopy: critical effects of peripheral bis-trimethylamination and cavity size.

Authors: Hatsuo Yamamura; Mikhail V Rekharsky; Yoko Ishihara; Masao Kawai; Yoshihisa Inoue
Journal: J Am Chem Soc Date: 2004-11-03 Impact factor: 15.419

10. Selective Recognition of d-Aldohexoses in Water by Boronic Acid-Functionalized, Molecularly Imprinted Cross-Linked Micelles.

Authors: Joseph K Awino; Roshan W Gunasekara; Yan Zhao
Journal: J Am Chem Soc Date: 2016-07-27 Impact factor: 15.419

19 in total

9. Sequence-Selective Recognition of Peptides in Aqueous Solution: A Supramolecular Approach through Micellar Imprinting.

Authors: Yan Zhao
Journal: Chemistry Date: 2018-06-29 Impact factor: 5.236

10. Molecularly Imprinted Micelles for Fluorescent Sensing of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs).

Authors: Likun Duan; Yan Zhao
Journal: React Funct Polym Date: 2020-10-18 Impact factor: 3.975

Sequence-Selective Binding of Oligopeptides in Water through Hydrophobic Coding.

1. Peptide and protein recognition by designed molecules.

2. Synthetic hosts via molecular imprinting--are universal synthetic antibodies realistically possible?

3. Sequence-dependent stereoselectivity in the binding of tetrapeptides in water by a flexible artificial receptor.

4. Selective protein capture by epitope imprinting.

5. Stereoselective recognition of the Ac-Glu-Tyr-OH dipeptide by pseudopeptidic cages.

6. Molecularly imprinted nanoparticles as tailor-made sensors for small fluorescent molecules.

7. Recognition, neutralization, and clearance of target peptides in the bloodstream of living mice by molecularly imprinted polymer nanoparticles: a plastic antibody.

8. A differential array of metalated synthetic receptors for the analysis of tripeptide mixtures.

9. Factors controlling the complex architecture of native and modified cyclodextrins with dipeptide (Z-Glu-Tyr) studied by microcalorimetry and NMR spectroscopy: critical effects of peripheral bis-trimethylamination and cavity size.

10. Selective Recognition of d-Aldohexoses in Water by Boronic Acid-Functionalized, Molecularly Imprinted Cross-Linked Micelles.

1. Selective Binding of Folic Acid and Derivatives by Imprinted Nanoparticle Receptors in Water.

2. Imprinted micelles for chiral recognition in water: shape, depth, and number of recognition sites.

3. Selective Binding of Complex Glycans and Glycoproteins in Water by Molecularly Imprinted Nanoparticles.

4. Water-Soluble Nanoparticle Receptors Supramolecularly Coded for Acidic Peptides.

5. Peptide-Binding Nanoparticle Materials with Tailored Recognition sites for Basic Peptides.

6. Synthetic lectins for selective binding of glycoproteins in water.

7. pH-Controlled Nanoparticle Catalysts for Highly Selective Tandem Henry Reaction from Mixtures.

8. Selective Binding of Dopamine and Epinephrine in Water by Molecularly Imprinted Fluorescent Receptors.

9. Sequence-Selective Recognition of Peptides in Aqueous Solution: A Supramolecular Approach through Micellar Imprinting.

10. Molecularly Imprinted Micelles for Fluorescent Sensing of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs).